AHA 2023 CardioNerds Conference Scholars Late-Breaking Video Collection

Published: 16 November 2023

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Part 1 | Session 7 of 10
AZALEA-TIMI 71: Abelcibab Vs Rivaroxaban in Patients with AF
Naima Maqsood, Christian Ruff

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Part 1 | Session 8 An Extended Duration Short-Interfering RNA Targeting Lp(a)
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Part 1 | Session 9 ARTESiA: Stroke Risk Reduction in Sub-Clinical AF: Apixaban vs Aspirin
Naima Maqsood, Jeff Healey
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Part 1 | Session 10 ARIES HM3: Avoidance of Aspirin with LVAD Devices
Mandeep Mehra, Christian Inchaustegui

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Part 1 | Session 1 ORBITA-2: PCI for Stable Angina Rasha Al-Lamee, Nazli Okumus, Christopher Rajkumar

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Part 1 | Session 2 SELECT: Effects of Semaglutide on Heart Disease & Stroke in Obese Patients A Michael Lincoff , Ahmed Ghoneem

16m 5s

Part 1 | Session 3 MINT: Myocardial Ischaemia & Transfusion Nazli Okumus, Jeffrey L Carson

11m 41s

Part 1 | Session 4 KARDIA-1: ALN-AGT01 in Patients With Mild-to Moderate Hypertension George L Bakris, Sukriti Banthiya

8m 35s

Part 1 | Session 5 CordiO App: Speech Analysis to Detect Worsening HF in ADHF Patients Hanad Bashir, William T Abraham

14m 32s

Part 1 | Session 6 AHA23: Presidential Advisory on Cardiovascular-Kidney-Metabolic Health Ramy Doss, Chiadi E Ndumele

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Overview

In 2023, we are excited to partner with @CardioNerds, a dynamic team dedicated to democratizing cardiovascular education. Experience a fresh perspective on the new data through an interview series featuring principal investigators and ambassadors from the CardioNerds family.

These interviews are supported by an educational grant from Novo Nordisk Inc. This content is not intended for UK HCPs.

More from this programme

Part 1

Radcliffe & Cardionerds @AHA23

10 sessions
ORBITA-2: PCI for Stable Angina	Watch now
SELECT: Effects of Semaglutide on Heart Disease & Stroke in Obese Patients	Watch now
MINT: Myocardial Ischaemia & Transfusion	Watch now
KARDIA-1: ALN-AGT01 in Patients With Mild-to Moderate Hypertension	Watch now
CordiO App: Speech Analysis to Detect Worsening HF in ADHF Patients	Watch now
AHA23: Presidential Advisory on Cardiovascular-Kidney-Metabolic Health	Watch now
AZALEA-TIMI 71: Abelcibab Vs Rivaroxaban in Patients with AF	Watch now
An Extended Duration Short-Interfering RNA Targeting Lp(a)	Watch now
ARTESiA: Stroke Risk Reduction in Sub-Clinical AF: Apixaban vs Aspirin	Watch now
ARIES HM3: Avoidance of Aspirin with LVAD Devices	Watch now

About the episode

AHA 23 - Dr Naima Maqsood, CardioNerds ambassador (Temple University Hospital, US) interviews Dr Christian Ruff (Brigham and Women's Hospital, US) on the late-breaking findings from the AZALEA-TIMI 71 randomized trial (Anthos Theraputics, Inc).

AZALEA-TIMI 71 aimed to evaluate the bleeding profile of abelcimab as compared to rivaroxaban in patients with atrial fibrillation who are at moderate to high risk of stroke. 1200 patients were enrolled in the trial, who were randomized to receive either the experimental group, or the active comparator group. The experimental arm was split into two treatment groups, where one group received a middle dose of abelcimab, and another received a high dose, both administered subcutaneously once per month. In the active comparator group, 20mg rivaroxaban was taken once per day.

Results showed a potent inhibition of factor XI, with over 95% inhibition over the dosing interval. A ≥2/3 reduction in bleeding as compared to rivaroxaban was observed in patients treated with abelcimab, with reduced major or clinically relevant non-major bleeding, major bleeding and major GI bleeding.

Recorded on-site at AHA Scientific Sessions 2023, Philadelphia.

Supported by an educational grant from Novo Nordisk Inc. This content is not intended for UK HCPs.

Faculty Biographies

Naima Maqsood

Naima Maqsood is a cardiology fellow at Temple University Hospital, Philadelphia. She graduated from the Aga Khan University Medical College in Pakistan. She completed Internal Medicine residency at Temple where she was part of the Medical Education Track. Her passions include electrophysiology, hemodynamics, exercise physiology and Medical Education. She is keen on pursuing a career in Cardiac Electrophysiology. Outside the hospital, she enjoys watching horror movies, learning about astrophysics and stargazing.