ACC 2023: Late-Breaking Science Video Collection

Published: 06 March 2023

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Our regular review series View from the Thoraxcenter, hosted by Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcentre, Erasmus MC, Rotterdam, NL) provides a critical analysis of the late-breaking and featured science results and spotlights impactful data. 


For a deeper look into the key clinical trial data revealed at ACC 23, Dr Harriette Van Spall (McMaster University, Hamilton, CA) interviews the principal investigators in her regular Late-Breaker Discussion Series


For short, concise coverage of the key data revealed, our accessible Expert Interviews were conducted with select faculty, focussing on the results, applicability and impact on future research. 

More from this programme

Part 3

View from the Thoraxcenter

In these concise episodes of View from the Thoraxcenter, Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcentre, Erasmus MC, Rotterdam, NL) offer their thoughts on the top late-breaking trials that will be presented at ACC 2023. 

About the episode

ACC.23/WCC — Late-breaker host, Dr Harriette Van Spall (McMaster University,CA) is joined by Dr Neha J Pagidipati (Duke University Medical Center, US) and Dr Christopher B Granger (Duke University Medical Center, US) to discuss the results of the COORDINATE-Diabetes trial.

The COORDINATE-Diabetes trial is testing a multifaceted intervention to improve the care of people with type 2 diabetes and atherosclerotic cardiovascular disease (ASCVD). 
The trial involves cardiology clinics in the US and provides a multi-disciplinary approach to care, including education for clinicians and patients, patient tracking, and monthly clinician calls to review cases. The primary outcome is the proportion of patients receiving all three types of recommended medication (high-intensity statin, ACEi/ARB, and SGLT2i or GLP1RA) at the last follow-up visit.
The trial showed that a coordinated, multifaceted intervention increased prescription of 3 groups of evidence-based therapies in adults with T2DM and ASCVD.

Recorded remotely from Hamilton and Durham, 2023. 

Faculty Biographies

Christopher B Granger

Christopher B Granger

Associate Professor of Medicine in the Division of Cardiology

Christopher B Granger, MD, is an Associate Professor of Medicine in the Division of Cardiology at Duke University. He is Director of the Cardiac Care Unit and Co-director of Cardiovascular Clinical Trials at the Duke Clinical Research Institute. He is a Fellow of the American College of Cardiology (ACC) and the European Society of Cardiology (ESC), Associate Editor of the American Heart Journal, and serves on the editorial boards of the Journal of the American College of Cardiology and the European Heart Journal. Dr Granger’s primary research interest is in the conduct and methodology of large randomized clinical trials in heart disease. He has co-authored over 200 peer-reviewed manuscripts.

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Harriette Van Spall

Harriette Van Spall

Associate Professor of Medicine, Director of E-Health and Virtual Care

Dr Harriette Van Spall is an Associate Professor of Medicine and cardiologist and serves as Director of E-Health at McMaster University, Canada. She completed her medical and postgraduate clinical training at the University of Toronto and earned a Master of Public Health degree at Harvard University, US. Dr Van Spall is a Canadian Institutes of Health Research-funded clinical trialist and researcher with a focus on heart failure, health services, and health disparities.

She has garnered more than $4 million in research funding, has won several research awards, and has published her work in high-impact medical journals. She is an invited speaker, media correspondent, and editorial board member active in peer review at several high-impact medications journals and grant funding agencies, including Canadian Institutes of Health Research and Heart and Stroke Foundation of Canada.

Dr Van Spall is an Editorial Board…

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Neha  Pagidipati

Neha Pagidipati

Assistant Professor of Medicine

Neha J Pagidipati is an Assistant Professor of Medicine and cardiovascular disease prevention specialist. Since 2011, she has conducted research on cardiometabolic disease prevention, lifestyle modification and weight management.  She is currently an NIH K12 scholar in Implementation and Dissemination Science. 

Dr Pagidipati is building the Duke Cardiometabolic Disease Prevention Program, which focuses on behavior change and risk factor management in patients with high risk of cardiovascular and metabolic diseases such as diabetes and obesity. 

Dr Pagidipati’s research grants include the COORDINATE-Diabetes Trial, to improve the quality of care for patients with diabetes and cardiovascular disease across the US, and QuBBD: Deep Poisson Methods for Biomedical Time-to-Event and Longitudinal Data. 

In addition, she is leading a large study within the Duke Health System to study heterogeneity within cardiovascular disease risk and…

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