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Author(s): W Kevin Tsai , Kathleen M Holohan , Kim Allan Williams Added: 3 years ago
Coronary artery disease (CAD) represents a tremendous financial and health burden as the leading cause of death in the US.1 Acute coronary syndrome and its subsequent manifestations, including heart failure and need for cardiac transplantation, are associated with significant morbidity and mortality. Hypertension, dyslipidemia, tobacco abuse, diabetes, chronic kidney disease, and family history… View more

Imaging & Diagnostics
Author(s): Soraya M Samii , Javier E Banchs Added: 3 years ago
Abstract The concept of using an implantable device to manage arrhythmias and heart failure started over 50 years ago. Since then, we have seen these devices improve patient outcomes from bradyarrhythmias, atrial fibrillation, ventricular arrhythmias, and heart failure. These devices are now standard of care in the management of patients and include pacemakers, implantable cardioverter… View more

Heart Failure

Electrophysiology & Arrhythmia
Pregnancy in Women with Congenital Heart Disease: A Guide for the General Cardiologist
Author(s): Catherine R Weinberg , Amier Ahmad , Boyangzi Li , et al Added: 3 years ago
Dyspnea, palpitations, edema, and fatigue are common symptoms during pregnancy. For women with congenital heart disease (CHD), it may be difficult to discern whether symptoms are due to normal pregnancy or underlying cardiac disease. Although most women with CHD tend to experience successful pregnancies, morbidity and mortality are significantly increased with more complex CHD lesions.1–6 Women… View more

Demographic
Author(s): John M Miller , Anil V Yadav Added: 3 years ago
In the nearly 30 years since Wellens et al. categorized most of the currently used electrocardiographic (ECG) criteria for distinguishing supraventricular tachycardia (SVT) with aberrant interventricular conduction from ventricular tachycardia (VT),1 there have been relatively infrequent and largely incremental enhancements to the art and science of making this distinction. In most published… View more

Electrophysiology & Arrhythmia
Author(s): Peter A McCullough Added: 3 years ago
Heart failure (HF) is a common condition and carries a considerable age-dependent all-cause mortality.1 As a leading cause of hospitalization in adults, ~50% of patients discharged with a diagnosis of HF are readmitted within six months, and the one-year mortality rate is 20% after an initial diagnosis is established. There is currently a chronic HF epidemic with a rapidly expanding prevalence… View more

Prevention & Chronic Conditions
HFA 23: REDWOOD-HCM-Cohort 4: Aficamten in symptomatic nHCM
Author(s): Ahmad Masri Added: 11 months ago
ESC-HFA 23 — We are joined by Dr Ahmad Masri (Oregon Health & Science University Medical Group, US) to discuss the findings from REDWOOD-HCM cohort 4 (NCT04219826). This study assessed the safety and tolerability of the selective inhibitor of cardiac myosin, aficamten (Cytokinetics) in patients with symptomatic nHCM. Cohort 4 included 41 patients. The data presented at HFA 23 shows that… View more

Heart Failure
ACC 22: Results from the PACIFIC AF Trial
Author(s): Manesh R Patel Added: 2 years ago
In this short interview from our coverage of ACC.22 late-breaking trials, Dr Manesh Patel (Duke Heart Center, US) discusses the multicentre, randomised, double-blind PACIFIC-AF trial (Bayer)(NCT04218266). The trial sought to determine the efficacy of the oral FXIa inhibitor asundexian and evaluate the safety of the drug, compared to the non-vitamin K oral anticoagulant (NOAC) apixaban, in… View more

Anticoagulation

Electrophysiology & Arrhythmia
Author(s): Astrid Apor , Andrea Nagy , Anikó Nagy , et al Added: 3 years ago
Abstract Mitral regurgitation (MR) is the most commonly found valvular lesion in echocardiography laboratories. Moderate and severe mitral regurgitation have proven to be associated with increased morbidity and mortality, and surgical reconstruction is recommended in severe cases whenever feasible. Three-dimensional echocardiography (3DE) is superior to conventional echocardiography in the… View more

Imaging & Diagnostics

Heart Failure
Foreword

Article

Author(s): Karen R Lui Added: 3 years ago
TodayÔÇÖs medical professional hardly goes a day without reading about or discussing the topic of 'disease managementÔÇÖ. While the term 'secondary preventionÔÇÖ has been around much longer, the newly emerging term refers to managing the chronic illness of large populations. The implications of this rapidly growing strategy are great for the future delivery of secondary prevention services to… View more

Heart Failure
Author(s): Richard Solomon Added: 3 years ago
Acute kidney injury (AKI) is a frequent occurrence in hospitalized patients and its overall incidence appears to be increasing. In addition, the number of patients in whom AKI is preceded by exposure to iodinated contrast is also increasing (see Figure 1). Patients who develop AKI in hospital are typically those undergoing major surgical procedures and individuals suffering from hemodynamic… View more

Imaging & Diagnostics