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Author(s): Meshal Soni , Edo Y Birati Added: 3 years ago
The history of documented heart failure in medical literature dates back as early as the late 1700s, when William Withering recognized the therapeutic use of foxglove in patients with “dropsy”. The extract from the foxglove plant contained the cardiac glycoside digitalis, and edema – known as “dropsy” – was described in patients we now presume had the clinical syndrome of heart failure.1 Over the… View more
Author(s): Nandita S Scott Added: 3 years ago
The US has the highest maternal mortality rate in the developed world, at an estimated 26.4 deaths per 100,000 live births. This rate is rising, although it is falling in other wealthy nations.1 Cardiovascular disease is a leading cause of maternal death, so cardiologists need to build on their knowledge and enhance their proficiency on the management of cardiovascular disease during pregnancy.2 … View more
Author(s): Lydia Taranto , Tabitha Moe Added: 3 years ago
As we approach 50 years since the original publication describing the Fontan procedure for palliation of single-ventricle congenital heart disease, we review the basics of Fontan circulation, and the current literature concerning long-term complications. Surgical interventions have allowed children with former lethal defects to survive into adulthood and we recognize that this has led to a new… View more
Author(s): Peter A McCullough Added: 3 years ago
Heart failure (HF) is a common condition and carries a considerable age-dependent all-cause mortality.1 As a leading cause of hospitalization in adults, ~50% of patients discharged with a diagnosis of HF are readmitted within six months, and the one-year mortality rate is 20% after an initial diagnosis is established. There is currently a chronic HF epidemic with a rapidly expanding prevalence… View more
Author(s): Melody Sherwood , Todd M Brown Added: 3 years ago
Cardiac rehabilitation (CR) refers to the provision of a wide range of secondary prevention services to patients with cardiovascular disease. Although exercise training is a core component of any CR program, modern comprehensive CR programs provide a comprehensive approach to disease modification including risk factor modification, nutritional counseling, weight management, and psychosocial… View more
Author(s): George Thomas , Emmanuel L Bravo Added: 3 years ago
Distinct hypertensive syndromes causing drug-resistant hypertension are increasingly being recognised. The ability to recognise these disorders has come as a result of a better understanding of their pathogenesis and the availability of sensitive and accurate diagnostic tools. The particular appeal of making the diagnosis centres around the potential curability of the hypertension, with… View more
Author(s): Raif Tawakol Added: 3 years ago
Many patients on statin therapy understandably develop a false sense of security. They enjoy a lowered level of low-desity lipoprotein (LDL) and a risk reduction of some 35%. However, two out of three patients develop a myocardial infarction (MI) while on a statin therapy. Statins often do not increase HDL levels to any substantial degree (except for Rosuvastatin, which increases high-density… View more