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Author(s): Maria Rosa Costanzo Added: 3 years ago
In the US, 90% of the one million annual hospitalizations for heart failure (HF) are due to volume overload.1,2 Hypervolemia contributes to HF progression and mortality. Guidelines recommend that therapy for HF patients be aimed at achieving euvolemia. Intravenous loop diuretics induce rapid diuresis that reduces lung congestion and dyspnea. However, the effectiveness of loop diuretics declines… View more
Author(s): Mitchell T Saltzberg Added: 3 years ago
Volume Overload in Heart Failure The burden of heart failure (HF) remains formidable in the US, with nearly one million annual hospital admissions and frequent outpatient visits to a variety of care providers.1 While HF outcomes have improved modestly over the past several decades, many patients still struggle to maintain a satisfactory quality of life.2 Implantable cardioverter–defibrillators… View more
Author(s): Sabu Thomas , Andrew J Boyle , Gary S Francis Added: 3 years ago
Acute decompensated heart failure (ADHF) is a syndrome defined by worsening fatigue, dyspnea, or edema that results from deteriorating heart function and usually leads to hospital admission or unscheduled medical intervention.1 Among patients over 65 years of age it remains the leading cause of hospital admission (>1 million admissions per year in the US alone), has an exceptionally high rate… View more
Research Area(s) / Expertise:

Heart Failure

Job title: Professor of Internal Medicine and Chief of the Division of Cardiovascular Medicine
Prof Abraham is a College of Medicine Distinguished Professor. He has been recognized as one of the “Best Doctors in America” for 18 consecutive years.His research has led to the approval/adoption of new heart failure therapies, including beta-blockers, natriuretic peptides, cardiac resynchronization therapy, ultrafiltration, implantable hemodynamic monitoring, transvenous phrenic nerve… View more
Job title: Consultant
Overview Dr David Sim is a senior consultant in the cardiology department at the National Heart Centre in Singapore. Academic History Royal College of Physicians (UK) diploma, 2004 Masters of Medicine (Internal Medicine), National University of Singapore, 2004 Bachelor of Medicine and Surgery, National University of Singapore, 2004 Career Overview Dr Sim is the… View more
Author(s): Jonathan N Johnson , Frank Cetta Added: 3 years ago
The last 60 years have seen significant changes in the care of congenital heart disease for both pediatric and adult patients. Increasing patient survival rates have widened the number and scope of potential patients seen by congenital cardiologists.1 These patients often undergo multiple surgeries, particularly since few lesions are truly ‘repaired.’ The majority of patients will have residua or… View more
Author(s): Karthiek R Narala , Thomas A LaLonde , Sohail Hassan , et al Added: 3 years ago
Chronic kidney disease (CKD) affects approximately 26 million people in the US.1 CKD is considered a coronary risk equivalent and also a risk factor for progression of cardiovascular disease (CVD).2 Cardiovascular death rates are 10–30 times higher in dialysis patients than in the general population.3 This increase in CKD patients is multifactorial and is now mainly considered via two pathways:… View more