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Job title: Clinical Senior Lecturer and Consultant Vascular Surgeon
Prakash Saha is a clinical senior lecturer at Kings College and honorary consultant endovascular surgeon at Guy's and St Thomas' Hospital, London, UK where he is the clinical lead for venous and lymphoedema surgery.Following the completion of his Wellcome Trust-funded PhD in 2012, Dr Saha has remained active in research and been awarded research grants from the Royal College of Surgeons, Royal… View more
Author(s): Kilmer S McCully Added: 3 years ago
Discovery of the Homocysteine Theory of Arteriosclerosis The American biochemist Vincent DuVigneaud discovered a new amino acid in 1932 by treating methionine with sulfuric acid. The structure of this amino acid is similar to cysteine, except for one extra carbon atom, hence the name homocysteine. Subsequent investigation established the role of homocysteine as an intermediate in sulfur amino… View more

Prevention & Chronic Conditions
Author(s): Sheldon M Goldberg , Jeffrey W Moses , Deepak K Parashara , et al Added: 3 years ago
Successful percutaneous coronary intervention (PCI) starts with a coronary guidewire that possesses specific characteristics designed to support advancement through various coronary vasculature anatomies. These wires can be grouped into four major categories based on their construction: stainless steel, hybrid, plastic, and niche. Steel guidewires can be further subdivided based on performance… View more

Standards & Guidelines

Intervention
Sherif Sultan
Research Area(s) / Expertise:

Vascular Disease and Surgery

Endovascular Techniques

 Job title: Professor of Vascular Surgery
Prof Sherif Sultan has more than three decades of vascular and endovascular surgery experience and a strong international reputation as one of the pioneers of open and minimally invasive vascular and endovascular techniques. He is the senior vascular surgeon at the West-Northwest Hospital group of the National Health Service Executive in Ireland. He founded the Western Vascular Institute, a… View more
HF 22: Ghrelin-HF: Intravenous Ghrelin In Patients with HFpEF
Author(s): Lars H Lund Added: 1 year ago
In this short interview from HF 22, Prof Lars Lund (Karolinska Institute, Stockholm, SE) joins us on-site to discuss the outcomes of the Ghrelin-HF study. This was a placebo controlled, randomised trial that evaluated the effects of intravenous ghrelin in patients with heart failure with preserved ejection fraction (HFpEF). Discussion Points: Aims of This Study Mechanism of Action Patient… View more

Heart Failure
AHA 2021 Late-breaker Discussion: The EMPULSE Trial
Author(s): Harriette Van Spall , Adriaan A Voors Added: 2 years ago
In this in-depth conversational interview, Late-breaker host Dr Harriette Van Spall (McMaster University, CA) meets PI, Prof Adriaan Voors (University Medical Center Groningen, NL) to discuss the EMPULSE trial. The aim of the trial was to evaluate empagliflozin compared with placebo among patients with acute decompensated heart failure. Presented first at AHA 2021, the trial showed that that… View more

Heart Failure
Author(s): Christopher M Kramer Added: 3 years ago
Cardiovascular Magnetic Resonance in Ischemic Heart Disease Left Ventricular Structure and Function at Rest The most fundamental quantitative measurements of the heart include those of ventricular size and function. Due to its high spatial and temporal resolution and the freedom to image in any plane, cardiovascular magnetic resonance (CMR) imaging is especially suited for this task… View more

Imaging & Diagnostics
Author(s): Stuart W Jamieson Added: 3 years ago
Pulmonary endarterectomy for the treatment of pulmonary hypertension from chronic thromboembolic disease is an uncommonly employed surgical procedure. However, this operation provides immediate and permanent relief of the pulmonary hypertension associated with the sequelae of unresolved pulmonary thromboembolic disease. Patients are generally not referred for operation because of a lack of… View more

Prevention & Chronic Conditions
Author(s): Jennifer Franke , Horst Sievert Added: 3 years ago
After having performed angioplasty in coronary and peripheral vascular disease with excellent results, carotid angioplasty was thought to be an opportunity to simplify the treatment of carotid stenosis. Up until then there was no apparent reason to protect patients against distal embolisation. With the development of carotid angioplasty and stenting, prevention of distal embolisation of… View more

Imaging & Diagnostics

Prevention & Chronic Conditions
ACC 22: Mavacamten in Patients with Severely Symptomatic Obstructive Hypertrophic Cardiomyopathy
Author(s): Milind Y Desai Added: 2 years ago
In this short summary interview, Dr Milind Y Desai (Cleveland Clinic, US) shares the findings from the VALOR-HCM trial (MyoKardia) (NCT04349072). This randomised, multicentre study was designed to assess the effect of mavacamten treatment on reducing the number of septal reduction therapy (SRT) procedures performed in subjects with symptomatic obstructive hypertrophic cardiomyopathy. Discussion… View more

Vascular Disease and Surgery