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Cardiac Toxicity of Cancer Chemotherapy

… As such, the acute and long-term toxicities of cancer therapies have become increasingly prominent as contributors … treatments, from conventional cytotoxic agents to newer targeted and immune-based therapies. Common manifestations of … , cardiotoxicity , anthracyclines , trastuzumab , targeted therapies , immune checkpoint blockade , Disclosure: …

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Article

Biological Therapies for Cardiac Arrhythmias

… Text Figures & Tables References Article Biological Therapies for Cardiac Arrhythmias Michael R Rosen , Register … therapy, a number of ion channel constructs targeted at specific ion channels are under assessment. All … be adequate expression in the cells to which delivery is targeted? Certainly, there is far more information to date …

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Article

Cardiac Toxicity of Cancer Chemotherapy

… in cancer survivors. Provide an overview of cancer therapies with the potential to cause significant cardiac … from conventional cytotoxic chemotherapies to newer targeted therapies and immune checkpoint inhibitors. Discuss the …

Type:

Webinar

Cardiovascular Biomarkers for Acute Coronary Syndromes Using a Multi-marker Strategy

… particularly robust benefit from aggressive anti-platelet therapies. 8 This is one example of how biomarkers might be … patients may have an inflammatory profileand eventually be targeted for very aggressive anti-inflammatory therapies. … neurohormonal activation have occurred and they might be targeted for very aggressive antagonism of those pathways …

Type:

Article

New Developments in the Management of Chronic Heart Failure

… Receptor Blockers in the Context of Other Medical Therapies Angiotensin-converting enzyme (ACE) inhibitors are …

Type:

Article

Bridging the Gap Between Scientific Evidence and Clinical Practice in the Management of Non-ST-segment Elevation Acute Coronary Syndromes

… newer therapeutic agents, and greater access to invasive therapies, as well as the burgeoning body of clinical trial … Accordingly, the available clinical evidence suggests that targeted co-administration of anticoagulant and antiplatelet … benefits of pairing appropriate patient groups with 'targeted' therapeutics, the routine use of bedside risk …

Type:

Article

Evolving Treatment Strategies for the Ablation of Chronic Atrial Fibrillation

… drugs. 1 The limitations associated with traditional AF therapies have fostered an interest in developing effective … and colleagues have suggested that CFAE should be targeted for successful catheter ablation. 21 CFAE areas may … or frequent premature atrial complexes that induce AF, are targeted. 25 The end-point of this extensive ablation …

Type:

Article

Stem Cells for the Ischemic Heart

… for cell delivery and/or mobilization, and cell types. Targeted conditions include advanced ischemic coronary … the fields that have undergone the most study and which therapies are most advanced. Acute Myocardial Infarction The … six days after acute infarction. This time window has been targeted as a result of both practical and theoretical …

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Article

Angiogenesis Inhibitors and Hypertension

… PubMed Chowdhury S, Spicer JF, Harper PG, Hypertension and targeted therapy, Targeted Oncology, 2006;1:104-8. Crossref Hurwitz H, …

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Article

Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Inhibition in Patients With or at High Risk of Coronary Heart Disease

… its affect on LDL-C have led to the rapid development of therapies targeted at reducing PCSK9 activity. Interference with the …

Type:

Article