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Author(s): Nico A Blom Added: 3 years ago
Cardiac resynchronization therapy (CRT) using biventricular pacing has been proven to be effective in adult patients with left ventricular (LV) systolic dysfunction and QRS prolongation. In this group of patients, CRT improves exercise tolerance, symptoms of heart failure and all-cause mortality.1 In addition, there is growing evidence that inter- and intra-ventricular dyssynchrony induced by… View more

Electrophysiology & Arrhythmia
Alicia Okines
Research Area(s) / Expertise:

Cardio-oncology

 Job title: Consultant Medical Oncologist, Royal Marsden Hospital, London, UK
Dr Alicia Okines is a consultant in medical oncology at the Royal Marsden NHS Foundation Trust and the team leader for the Breast Cancer Systemic Therapy Trials team.Dr Okines studied pharmacology at the University of Sheffield, where she also pursued her medical training. Throughout her oncology residency at The Royal Marsden Hospital and the Institute of Cancer Research, she earned an MD(Res),… View more
HRS 21: Results from the STROKE-VT Trial
Author(s): Dhanunjaya Lakkireddy Added: 2 years ago
Dr Dhanunjaya Lakkireddy (Kansas City Heart Rhythm Institute, Overland Park, KS, US) sits down to discuss the findings of the STROKE-VT Trial, which investigated the use of aipaxaban in reducing blood clots and stroke risk after an ablation procedure. Questions: 1. Please summarise the aim, study design and endpoints? 2. What were your major findings? 3. What further research is required? 4… View more

Anticoagulation

Electrophysiology & Arrhythmia
Author(s): Steven R Sigman Added: 3 years ago
Although less common than other forms of cardiomyopathy, cardiac sarcoidosis (CS), both as part of a systemic process and in its isolated form, is an important, and increasingly recognized disorder. This is felt to be due, in part, to advances in cardiac imaging and heightened awareness of the disorder.1,2 CS is associated with high rates of morbidity and mortality, including sudden cardiac death… View more

Imaging & Diagnostics
ESC 23: The PUSH-AHF Study
Author(s): Paulus Kirchhof Added: 7 months ago
ESC 2023 — Prof Paulus Kirchhof (University Heart & Vascular Center Hamburg, DE) discusses the findings of the NOAH-AFNET 6 trial (NCT02618577). NOAH-AFNET 6 (Atrial Fibrillation Network, Daiichi Sankyo Europe) was an investigator-initiated, prospective, randomised trial aiming to demonstrate that oral anticoagulation using the NOAC edoxaban is superior to current therapy in stroke prevention,… View more

Anticoagulation

Heart Failure
Single-Ventricle Physiology
Author(s): Lydia Taranto , Tabitha Moe Added: 3 years ago
As we approach 50 years since the original publication describing the Fontan procedure for palliation of single-ventricle congenital heart disease, we review the basics of Fontan circulation, and the current literature concerning long-term complications. Surgical interventions have allowed children with former lethal defects to survive into adulthood and we recognize that this has led to a new… View more

Heterogeneous Populations
Advanced Management Options for Massive and Submassive Pulmonary Embolism
Author(s): Sonika Malik , Anju Bhardwaj , Matthew Eisen , et al Added: 3 years ago
Pulmonary embolism (PE) is a common and serious manifestation of venous thromboembolism (VTE) and is an important cause of morbidity and mortality in the US. The incidence is estimated to be 50 per 100,000 but increases to 500 per 100,000 in the elderly.1 There is a wide spectrum of clinical severity with mortality estimates of 1–2 % in stable individuals and up to 30 % in patients presenting… View more

Anticoagulation

Intervention
Author(s): Yaser Nemshah , Alex Clavijo , Gyanendra Sharma Added: 3 years ago
Amyloidosis is a heterogenous group of disorders that develops secondary to the deposition of abnormally folded proteins, amyloid fibrils, in the extracellular space. Amyloidosis is classified according to the type of the precursor protein that results in the formation of amyloid fibrils. It can be inherited or acquired, and can involve multiple organs, including the heart. Amyloidosis that… View more

Heart Failure
Pregnancy in Women with Congenital Heart Disease: A Guide for the General Cardiologist
Author(s): Catherine R Weinberg , Amier Ahmad , Boyangzi Li , et al Added: 3 years ago
Dyspnea, palpitations, edema, and fatigue are common symptoms during pregnancy. For women with congenital heart disease (CHD), it may be difficult to discern whether symptoms are due to normal pregnancy or underlying cardiac disease. Although most women with CHD tend to experience successful pregnancies, morbidity and mortality are significantly increased with more complex CHD lesions.1–6 Women… View more

Demographic
Coarctation: A Review
Author(s): Marc G Cribbs Added: 3 years ago
The incidence of congenital heart disease (CHD) is slightly less than 1% of all live births.1 With extensive medical and surgical innovation over the past 50 years, and the high-quality care received in childhood, 85–90% of children with CHD in the US survive into adulthood. As a result, the number of adults with congenital heart defects in the US now exceeds 1 million, with a projected continued… View more

Heterogeneous Populations