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3 years ago
Cardiocerebral resuscitation (CCR) is a relatively new approach to the resuscitation of patients with out-of-hospital cardiac arrest (see Figure 1). By 2003, both the accumulated resuscitation research data and our own local clinical experience in Tucson, Arizona clearly indicated that interruptions of chest compressions had a negative effect on survival. Accordingly, in November 2003 in co…
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3 years ago
2D echocardiography (2DE) is a common diagnostic and treatment planning tool in clinical cardiology, especially for the assessment of left ventricular (LV) volume and function. However, traditional 2DE is severely limited by its dependence on geometrical assumptions, which can lead to inaccuracies in volume quantification.1 Because 3D echocardiographic (3DE) imaging eliminates geometrical…
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3 years ago
The pump function of the heart resides on two main abilities that allow the entire organism to cope with and face different physiological circumstances from sleep to intense physical exercise of sport activities:
a) diastolic function, defined as the ability of the ventricles to relax and to accept the normal stroke volume at the low pressures existing in the systemic and pulmonary veins; and
…
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3 years ago
Heart disease, specifically coronary artery disease (CAD), is the leading cause of death and disability among both men and women in the US. Reductions in blood supply due to narrowings of the arteries that supply the heart muscle with oxygen and nutrients (coronary arteries) result in chest pain and shortness of breath and may lead to permanent scarring of the heart muscle, as in the setting of a…
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3 years ago
Coronary angioplasty has revolutionized the treatment of coronary artery disease. Over the past two decades the field has seen numerous innovations in an attempt to perfect the percutaneous management of coronary atherosclerotic disease. The development of coronary stenting was a major advance in preventing elastic recoil and treating dissections following balloon angioplasty.1 Unfortunately,…
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Dr Lindsay E Clegg
Job title: Modeling Scientist, Clinical Pharmacology and Quantitative Pharmacology
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6 months ago
Added:
3 years ago
Contrast echocardiography (CE) is 40 years old this year. Gamiak and Shah first described the use of ultrasound (US) contrast in 1968 during the early days of M-mode echocardiography.1 In that study, US contrast was produced by inadvertently introducing air bubbles in the indocyanine green solution that was injected into the left heart during cardiac catheterisation and observing its appearance…
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3 years ago
In the US, 90% of the one million annual hospitalizations for heart failure (HF) are due to volume overload.1,2 Hypervolemia contributes to HF progression and mortality. Guidelines recommend that therapy for HF patients be aimed at achieving euvolemia. Intravenous loop diuretics induce rapid diuresis that reduces lung congestion and dyspnea. However, the effectiveness of loop diuretics declines…
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3 years ago
The approach to the treatment of a variety of cardiovascular disorders has undergone remarkable change over the past two decades. The use of both percutaneous interventions in patients with acute myocardial infarction and automatic implantable cardiodefibrillators in patients with ventricular arrhythmias represent important examples. The cardiology community is currently in the process of another…
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