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Author(s): Rhian E Davies , J Dawn Abbott Added: 3 years ago
Percutaneous Coronary Intervention for Clinical Syndromes Stable Angina The primary benefit of percutaneous coronary intervention (PCI) over medical therapy in patients with stable angina is the improved quality of life. The PCI in stable angina (ORBITA) trial was the first sham-controlled trial of PCI where 200 medically optimized patients with single vessel disease were randomized to PCI or… View more
Author(s): Jorge Silva Enciso , Eric Adler , Barry H Greenberg Added: 3 years ago
Advanced heart failure (AHF) affects approximately 5–10 % of the current 6.6 million people living with heart failure, having a higher incidence in those above 65 years of age.1 The presence of the disease is associated with 50–80 % mortality at 1 year, indicating the need for innovative therapies to manage the burden of this disease. Heart transplantation is the gold standard for AHF, although… View more
Author(s): Matthew J Budoff Added: 3 years ago
Cardiac computed tomography (CT) has evolved greatly over the last 20 years. This article reviews its current clinical uses, and describes some of the potential for even greater utility in the near future. Electron beam tomography (EBT) was developed 20 years ago specifically for cardiac imaging. Although the technique can quantify ventricular anatomy and function1 as well as myocardial… View more
Author(s): Srinivas Murali Added: 3 years ago
Introduction Nearly five million Americans suffer from heart failure, with 550,000 new cases diagnosed with this disease each year. Heart failure is responsible for 11 million office visits and over 3.5 million hospitalizations per year in the US, with a total bill of US$23 billion spent annually on treatment. About 250,000 people in the US suffer from severe, end-stage heart failure (NYHA Class… View more
Author(s): Robert C Hendel Added: 3 years ago
Heart disease, specifically coronary artery disease (CAD), is the leading cause of death and disability among both men and women in the US. Reductions in blood supply due to narrowings of the arteries that supply the heart muscle with oxygen and nutrients (coronary arteries) result in chest pain and shortness of breath and may lead to permanent scarring of the heart muscle, as in the setting of a… View more
Author(s): Robert C Hendel Added: 3 years ago
Background Heart disease, specifically coronary artery disease (CAD), is the leading cause of death and disability among both men and women in the US. Reductions in blood supply due to narrowings of the arteries that supply the heart muscle with oxygen and nutrients (coronary arteries) result in chest pain and shortness of breath and may lead to permanent scarring of the heart muscle, as in the… View more
Job title: Director of Coronary Imaging and Atherosclerosis Research
Dr Yohinobu Onuma, MD, PhD is a leading expert in the field of noninvasive and invasive coronary imaging and novel coronary devices such as bioresorbable scaffolds. His expertise includes quantitative coronary angiography (2-dimensional, 3-dimensional and bifurcation-dedicated), Syntax Score and multi-slice computed tomography. He holds the position of professor of interventional cardiology at… View more
Author(s): Lydia Taranto , Tabitha Moe Added: 3 years ago
As we approach 50 years since the original publication describing the Fontan procedure for palliation of single-ventricle congenital heart disease, we review the basics of Fontan circulation, and the current literature concerning long-term complications. Surgical interventions have allowed children with former lethal defects to survive into adulthood and we recognize that this has led to a new… View more
Author(s): Ajit Yoganathan , Fotis Sotiropoulos Added: 3 years ago
Background Since the first successful implantation of a prosthetic heart valve four decades ago, over 50 different designs have been developed including both mechanical and bioprosthetic valves. Today, with over 200,000 implants worldwide each year, the most widely implanted design is the mechanical bileaflet prosthesis. Several other mechanical valves are currently available and many of them… View more