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Author(s): Robert H Christenson Added: 3 years ago
Accurate and timely biochemical marker testing for aiding the diagnosis of myocardial infarction (MI) has been important for the appropriate disposition and treatment of patients for the past several decades. Creatine kinase (CK) muscle and brain (CK-MB) mass and myoglobin measurements were the standard up to the mid-1990s, when assays for the cardiac-specific isoforms of troponin I and troponin… View more

MI/ACS
Justin Beilby
Job title: Deputy Vice Chancellor Research
Personal History Prof Justin Beilby is a researcher who currently works as the Deputy Vice Chancellor Research for Torrens University Australia. He is based in Adelaide, Australia. Academic History Prof Justin Beilby completed his Bachelor of Medicine, Bachelor of Surgery, Master of Public Health and Doctor of Medicine qualifications at the University of Adelaide, Australia. … View more
Author(s): Debra Green , Jack E Ansell , Stephan Moll Added: 3 years ago
Oral anticoagulants are one of the most common causes of drug-induced adverse events.1 Expert dose management, which keeps the patient within a narrow therapeutic international normalized range (INR), is required to avoid adverse events and optimize therapy. Anticoagulation clinic (ACC) management has been shown to improve outcomes compared with the routine management provided by physicians,2 but… View more

Anticoagulation

Prevention & Chronic Conditions
Author(s): Rita Paniccia Added: 3 years ago
The goal of platelet function tests used in cardiac catheterization laboratories and intensive cardiac units is to guide antiplatelet therapy to the optimal dose for the prevention or treatment of thrombosis, minimizing hemorrhagic side effects in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI).1–4 Platelet function tests measure the platelet capacity to… View more

Anticoagulation

Prevention & Chronic Conditions
Author(s): Judd E Hollander Added: 3 years ago
Ischemic heart disease is the leading cause of death among adults and one of the most common reasons for emergency department (ED) visits across the US. There are approximately five to seven million ED visits for acute chest pain syndromes annually; however, only 5% of these patients are ultimately diagnosed with acute myocardial infarction (AMI) and an additional 10% have non-AMI acute coronary… View more

MI/ACS
Platelet Function Testing and Genotyping in Complex PCI
Author(s): Athanasios Moulias , Angeliki Papageorgiou , Dimitrios Alexopoulos Added: 2 years ago

Intervention
Author(s): Shanmugam Uthamalingam , James L Januzzi Added: 3 years ago
Amino-terminal pro-B-type natriuretic peptide (NT-proBNP) is one of the natriuretic peptide family of hormones that play a vital role in the regulation of circulatory volume and pressure, reducing activity of the renin–angiotensin–aldosterone system and minimising myocardial fibrosis in the setting of heart muscle stretch. Therefore, natriuretic peptides exert favourable effects on the heart in… View more

Heart Failure

MI/ACS
ICU Management of Cardiogenic Shock
Author(s): Shahana Uddin , Rathai Anandanadesan , Richard Trimlett , et al Added: 1 year ago

Imaging & Diagnostics

Heart Failure
Author(s): James L Januzzi Added: 3 years ago
The use of natriuretic peptide testing has dramatically risen recently, in recognition of the value of these blood tests for assisting in the evaluation of patients with suspected heart failure (HF). B-type natriuretic peptide (BNP) is formed as a consequence of production of a 108-amino-acid precursor peptide that is synthesised within the cardiomyocyte; this 'pro-BNP108' is subsequently cleaved… View more

Heart Failure

Prevention & Chronic Conditions
Author(s): James L Januzzi Added: 3 years ago
The use of natriuretic peptide testing has dramatically risen recently, in recognition of the value of these blood tests for assisting in the evaluation of patients with suspected heart failure (HF). B-type natriuretic peptide (BNP) is formed as a consequence of production of a 108-amino-acid precursor peptide that is synthesised within the cardiomyocyte; this 'pro-BNP108' is subsequently cleaved… View more

Imaging & Diagnostics

Heart Failure