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Author(s): Rebecca L Attridge , Rebecca D Moote , Deborah J Levine Added: 3 years ago
Pulmonary hypertension is classified into five groups by the World Health Organization (WHO). Group 1, pulmonary arterial hypertension (PAH), is a progressive disease characterized by an elevation in pulmonary arterial pressure and pulmonary vascular resistance that may progress to right heart dysfunction and failure.1 PAH is defined as a mean pulmonary artery pressure (mPAP) ≥25 mmHg at rest,… View more

Heart Failure

Prevention & Chronic Conditions
Author(s): Hossein-Ardeschir Ghofrani , Ralph T Schermuly , Norbert Weissmann , et al Added: 3 years ago
Pulmonary arterial hypertension (PAH) has an estimated prevalence of 15–25 cases/million population.1 This chronic, progressive disease is defined by a mean pulmonary arterial pressure >25mmHg in conjunction with normal pulmonary capillary wedge pressure <15mmHg.2 The disease is characterized by increased vascular resistance of the pulmonary microvasculature, ultimately resulting in right… View more

Prevention & Chronic Conditions
Author(s): Michael D McGoon Added: 3 years ago
Pulmonary hypertension (PH) is a hemodynamic condition defined by pulmonary arterial systolic pressure (PASP) above an upper limit of 35mmHg, or by pulmonary arterial mean pressure (PAMP) exceeding 25mmHg at rest. Pulmonary arterial hypertension (PAH) is present when pre-capillary pulmonary vascular pressure is elevated in the absence of pulmonary capillary wedge pressure >15mmHg, such as that… View more

Prevention & Chronic Conditions
Author(s): Mark Huffman , Vallerie V McLaughlin Added: 3 years ago
Idiopathic pulmonary arterial hypertension (formerly referred to as primary pulmonary hypertension) is an uncommon yet progressively fatal disease defined by the presence of mean pulmonary artery pressure greater than 25mmHg at rest or greater than 30mmHg with exercise as tested by right heart catheterization in the absence of other etiologies for pulmonary hypertension. Across several studied… View more

Prevention & Chronic Conditions
Author(s): Mark Huffman , Vallerie V McLaughlin Added: 3 years ago
Idiopathic pulmonary arterial hypertension (formerly referred to as primary pulmonary hypertension) is an uncommon yet progressively fatal disease defined by the presence of mean pulmonary artery pressure greater than 25mmHg at rest or greater than 30mmHg with exercise as tested by right heart catheterization in the absence of other etiologies for pulmonary hypertension. Across several studied… View more

Vascular Disease and Surgery

Prevention & Chronic Conditions
Author(s): Omar A Minai Added: 3 years ago
Pulmonary arterial hypertension (PAH) is a disorder of the pulmonary circulation in which elevated pressure in the pulmonary vascular circuit, when severe, can lead to right heart failure and eventually cause death. The last three decades have seen significant advances in our understanding of this group of disorders and, with this understanding, the development of novel therapies to assist in… View more

Prevention & Chronic Conditions
Author(s): Omar A Minai Added: 3 years ago
Pulmonary arterial hypertension (PAH) is a disorder of the pulmonary circulation in which elevated pressure in the pulmonary vascular circuit, when severe, can lead to right heart failure and eventually cause death. The last three decades have seen significant advances in our understanding of this group of disorders and, with this understanding, the development of novel therapies to assist in… View more

Prevention & Chronic Conditions
Author(s): Mark Huffman , Vallerie V McLaughlin Added: 3 years ago
Idiopathic pulmonary arterial hypertension (formerly referred to as primary pulmonary hypertension) is an uncommon yet progressively fatal disease defined by the presence of mean pulmonary artery pressure greater than 25mmHg at rest or greater than 30mmHg with exercise as tested by right heart catheterization in the absence of other etiologies for pulmonary hypertension. Across several studied… View more

Electrophysiology & Arrhythmia
Author(s): Mark Huffman , Vallerie V McLaughlin Added: 3 years ago
Idiopathic pulmonary arterial hypertension (formerly referred to as primary pulmonary hypertension) is an uncommon yet progressively fatal disease defined by the presence of mean pulmonary artery pressure greater than 25mmHg at rest or greater than 30mmHg with exercise as tested by right heart catheterization in the absence of other etiologies for pulmonary hypertension. Across several studied… View more

Prevention & Chronic Conditions
Author(s): Srinivas Murali Added: 3 years ago
Introduction Pulmonary arterial hypertension (PAH) is a disease affecting the pulmonary vascular endothelium of the small pulmonary vessels that causes progressive elevations in pulmonary vascular resistance, leading to right ventricular failure and death. PAH can result from a number of causes or associated risk factors. A clinical classification (Evian classification) was developed in 1993 and… View more

Electrophysiology & Arrhythmia