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Author(s): Michela Faggioni , Michael C Gibson , Roxana Mehran Added: 3 years ago
The use of non-vitamin K antagonist oral anticoagulants (NVKA) has revolutionized the antithrombotic treatment of patients with atrial fibrillation (AF), finally freeing them of the inconvenience and expense of international normalized ratio measurements. However, add to the equation the presence of coronary artery disease requiring percutaneous coronary intervention (PCI) with stent placement… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Antithrombotic Therapy in Complex PCI Patients Under OAC
Author(s): Despoina-Rafailia Benetou , Panayotis K Vlachakis , Charalampos Varlamos , et al Added: 2 years ago

Anticoagulation

Intervention
Author(s): Leo Buckley , Ahmed Aldemerdash Added: 3 years ago
Cardiovascular disease is the leading cause of death in the US.1,2 Although advances in the prevention and treatment of cardiovascular disease have contributed to a decline in mortality rates, this favorable trend has slowed over the past several years.3 Recently, however, a revival of cardiovascular drug development has introduced new treatment options to the market, with several promising… View more

Prevention & Chronic Conditions
ESC 23: The PUSH-AHF Study
Author(s): Paulus Kirchhof Added: 7 months ago
ESC 2023 — Prof Paulus Kirchhof (University Heart & Vascular Center Hamburg, DE) discusses the findings of the NOAH-AFNET 6 trial (NCT02618577). NOAH-AFNET 6 (Atrial Fibrillation Network, Daiichi Sankyo Europe) was an investigator-initiated, prospective, randomised trial aiming to demonstrate that oral anticoagulation using the NOAC edoxaban is superior to current therapy in stroke prevention,… View more

Anticoagulation

Heart Failure
Best Practices in Pharmacotherapy for Acute Coronary Syndromes
Author(s): Robert Barcelona Added: 1 year ago

Anticoagulation

MI/ACS
Antiplatelet and Anticoagulation Therapy in ACS
Author(s): Colin T Phillips , Michael C Gavin Added: 3 years ago
Acute coronary syndrome (ACS) occurs most often when a vulnerable intracoronary plaque ruptures or erodes to expose a prothrombotic core, precipitating thrombus formation by way of platelet activation,1–3 The spectrum of ACS includes non-ST segment-elevation (NSTE) ACS, where a vulnerable plaque threatens downstream coronary perfusion manifest as an increase in symptom frequency and/or duration … View more

Prevention & Chronic Conditions

MI/ACS
Author(s): Donald E Cutlip Added: 3 years ago
Stent thrombosis has been recognized as a serious complication of coronary stent placement since the procedure was first reported in the 1980s.1 Subsequent aggressive peri-procedural anti-thrombotic strategies with inpatient transition to warfarin reduced the risk to about 3.5 % for subacute (30-day) stent thrombosis,2,3 a rate that would be unacceptable by current standards and did not account… View more

Prevention & Chronic Conditions

Intervention
Major Cardiovascular Advances: Highlights from the 2019 American College of Cardiology Annual Scientific Session
Author(s): Hisham A Badreldin , Khalid bin Saleh , Majed Al-Yami Added: 3 years ago
WRAP-IT The Worldwide Randomized Antibiotic Envelope Infection Prevention Trial (WRAP-IT) was a prospective multicenter study to determine the safety and efficacy of an absorbable surgical mesh envelope containing two antibiotics (minocycline and rifampin) in reducing infection incidence in patients with cardiac implantable electronic devices compared to standard care.1 Approximately 7,000… View more

Prevention & Chronic Conditions
Author(s): Jeffrey L Turner , Nassir F Marrouche Added: 3 years ago
The incidence of AF is on the rise.1–3 This is secondary not only to increasing prevalence but also a focus on increased recognition of occult AF for primary thromboembolic (TE) prevention.4 How we identify and treat these patients with AF is constantly in flux. While it is possible that a novel procedure or antiarrhythmic drug could create sweeping changes in AF management overnight, here we… View more

Electrophysiology & Arrhythmia
Single-Ventricle Physiology
Author(s): Lydia Taranto , Tabitha Moe Added: 3 years ago
As we approach 50 years since the original publication describing the Fontan procedure for palliation of single-ventricle congenital heart disease, we review the basics of Fontan circulation, and the current literature concerning long-term complications. Surgical interventions have allowed children with former lethal defects to survive into adulthood and we recognize that this has led to a new… View more

Heterogeneous Populations