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AHA 25: The CORALreef HeFH Trial
Author(s): Christie Ballantyne Added: 4 weeks ago
AHA Scientific Sessions 2025 - Dr Christie Ballantyne (Baylor College of Medicine, Houston, TX, US) discusses findings from the CORALreef HeFH trial, examining the efficacy and safety of enlicitide decanoate, an oral PCSK9 inhibitor, in adults with heterozygous familial hypercholesterolemia.This Phase 3, randomized, double-blind, placebo-controlled study evaluated 303 participants with… View more

Cardiovascular Renal Metabolic
SGLTi and GLP-1 in HF
Author(s): Jose Lopez , Tracy Makuvire , Jonathan D Davis , et al Added: 6 months ago

Cardiovascular Renal Metabolic

Heart Failure
ESC 23: LIBerate-HeFH Study
Author(s): Frederick Raal Added: 2 years ago
ESC 23 — Prof Frederick Raal (University of the Witwatersrand, Johannesburg, SA) outlines the late-breaking results from the LIBerte-HeFH study (NCT04797104). The phase III LIBerte-HeFH study (LIB Therapeutics LLC) aimed to assess the effectiveness of PCSK9-inhibitor Ierodalcibep (LIB003) in reducing low-density lipoprotein cholesterol (LDL-C) in 300mg doses administered subcutaneously in… View more

Inherited and Congenital Cardiac Conditions

Prevention & Chronic Conditions
Lifestyle Modification after PCI
Author(s): Nicholas Nguyen , Katherine C Michelis Added: 11 months ago

Prevention & Chronic Conditions
The Evolving Treatment Landscape for HFpEF in Cardiac Amyloidosis
Author(s): Added: 4 weeks ago
AHA Scientific Sessions 2025 - Dr Sarah Cuddy (Brigham and Women's Hospital, US) joins us to discuss the role of non-disease modifying treatments including SGLT2 inhibitors, mineralocorticoid receptor antagonists, GLP-1 receptor agonists, and implantable hemodynamic monitors in cardiac amyloidosis, and what this means for managing heart failure in this unique patient population.Interview… View more

Heart Failure
Important Gaps in Heart Failure Care
Author(s): Zara Latif , Tracy Makuvire , Sarah Schroeder , et al Added: 1 week ago

Heart Failure
Research Area(s) / Expertise: Job title: Clinical Lecturer (Institute of Cardiovascular & Medical Sciences)
Kieran Docherty studied medicine at the University of Glasgow from 2005-2011. He is a Cardiology Specialist Registrar in the West of Scotland Deanery and a Clinical Research Fellow at the Institute of Cardiovascular and Medical Sciences at the University of Glasgow.He is undertaking a PhD examining the effects of neprilysininhibition on left ventricular remodelling. View more
AHA 25 Late-breaking Discussion: The VESALIUS-CV Trial
Author(s): Erin A Bohula , Harriette Van Spall Added: 3 weeks ago
AHA Scientific Sessions 2025 – Late-breaker host Dr Harriette Van Spall (McMaster University, CA) is joined by Dr Erin A Bohula (Brigham & Women's Hospital, US) to discuss the primary results of the VESALIUS-CV trial, a large-scale, phase 3, double-blind, randomised, placebo-controlled study sponsored by Amgen.The VESALIUS-CV trial (NCT03872401) evaluated the impact of evolocumab, a PCSK9… View more

MI/ACS

Prevention & Chronic Conditions
AHA 25: MAPLE-HCM Responder Analysis
Author(s): Andrew Wang Added: 4 weeks ago
AHA Scientific Sessions 2025 – MAPLE-HCM responder analysis shows aficamten monotherapy led to greater treatment effect when compared to metoprolol monotherapy.Dr Andrew Wang (Duke University Medical Center, Durham, NC, US) presents a responder analysis from the MAPLE-HCM trial (NCT05767346), examining clinical responses to aficamten monotherapy versus metoprolol in patients with obstructive… View more

Heart Failure
Antoni Bayés-Genís
Job title: Head of the Cardiology Department
Antoni Bayés-Genís is Head of the Heart Institute at the University Hospital Germans Trias i Pujol in Barcelona, and Professor of Cardiology at the Universitat Autònoma de Barcelona in Barcelona, Spain.Prof Bayés-Genís is an expert on biomarker, including natriuretic peptides ST2 and neprilysin, having lectured on the subject at numerous international meetings and generated research data that… View more