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Invasive Evaluation for Coronary Vasospasm
Author(s): Jingwen Huang , Rebecca Steinberg , Matthew J Brown , et al Added: 10 months ago

MI/ACS

Intervention
Antithrombotic Therapy in Chronic Total Occlusion Interventions
Author(s): Iosif Xenogiannis , Charalampos Varlamos , Despoina-Rafailia Benetou , et al Added: 2 years ago

Intervention
Author(s): Steve Attanasio , Raed Al Dallow , Sandeep Nathan Added: 3 years ago
While acute coronary syndromes inclusive of ST-elevation myocardial infarction (STEMI) have been described in patients with polycythemia vera (PCV), optimal pharmacologic and interventional management strategies in the setting of drastically elevated platelet counts remain unclear.1 To our knowledge this is the first reported case of STEMI with massive thrombus burden in a patient with PCV… View more

MI/ACS
The Role of Hemodynamic Support in High-risk Percutaneous Coronary Intervention
Author(s): Charles Simonton , Craig Thompson , Jason R Wollmuth , et al Added: 3 years ago
Coronary artery disease (CAD) is a leading cause of morbidity and mortality globally, despite advances in medical and preventive therapy. It is estimated that 18.2 million adults in the US have CAD, with 720,000 Americans projected to have a first hospitalization for MI or CAD death this year.1 Treatment of patients with symptomatic CAD includes guideline-directed medical therapy and coronary… View more

Intervention
Author(s): Sara C Martinez , Sharonne N Hayes Added: 3 years ago
Pregnancy is a physiologic challenge, with significant hormonal, metabolic, and hemodynamic changes. Cardiac output is objectively increased by the fifth week after the last menstrual period and continues to grow by approximately 45 % by 24 weeks in the normal, singleton pregnancy. This is facilitated by elevations in heart rate and stroke volume and a decrease in systemic vascular resistance… View more

Heart Failure

Prevention & Chronic Conditions
Platelet Function Testing and Genotyping in Complex PCI
Author(s): Athanasios Moulias , Angeliki Papageorgiou , Dimitrios Alexopoulos Added: 2 years ago

Intervention
Author(s): Sandeep Nathan , Rajiv Swamy Added: 3 years ago
The spectrum of acute coronary syndromes (ACS) encompasses a broad array of clinical characteristics and risk strata, ranging from unstable angina (UA) and non-ST-segment elevation myocardial infarction (NSTEMI) to ST-segment elevation myocardial infarction (STEMI) and sudden cardiac death (SCD). In this article, UA and NSTEMI will be considered together as non-ST-segment elevation acute coronary… View more

Anticoagulation
Author(s): Yaser Nemshah , Alex Clavijo , Gyanendra Sharma Added: 3 years ago
Amyloidosis is a heterogenous group of disorders that develops secondary to the deposition of abnormally folded proteins, amyloid fibrils, in the extracellular space. Amyloidosis is classified according to the type of the precursor protein that results in the formation of amyloid fibrils. It can be inherited or acquired, and can involve multiple organs, including the heart. Amyloidosis that… View more

Heart Failure
Author(s): Atsushi Sakamoto , Anne Cornelissen , Yu Sato , et al Added: 2 years ago

Vascular Disease and Surgery
Author(s): Kilmer S McCully Added: 3 years ago
Discovery of the Homocysteine Theory of Arteriosclerosis The American biochemist Vincent DuVigneaud discovered a new amino acid in 1932 by treating methionine with sulfuric acid. The structure of this amino acid is similar to cysteine, except for one extra carbon atom, hence the name homocysteine. Subsequent investigation established the role of homocysteine as an intermediate in sulfur amino… View more

Prevention & Chronic Conditions