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Author(s): Peter A McCullough Added: 3 years ago
Heart failure (HF) is a common condition and carries a considerable age-dependent all-cause mortality.1 As a leading cause of hospitalization in adults, ~50% of patients discharged with a diagnosis of HF are readmitted within six months, and the one-year mortality rate is 20% after an initial diagnosis is established. There is currently a chronic HF epidemic with a rapidly expanding prevalence… View more
Author(s): Raymond B Fohtung , Michael W Rich Added: 3 years ago
Atrial fibrillation (AF) is the most common clinically significant arrhythmia, with an overall prevalence of approximately 1 % in the general population.1 An estimated 2.3 million adults in the US have AF, and this number is projected to increase to 5.6 million by 2050.1 The most clinically important complication from AF lies in the risk for cardiac thrombus formation and systemic embolism… View more
Author(s): G Hamilton Baker , Girish S Shirali Added: 3 years ago
Congenital heart disease affects approximately 0.8% of the population.1 It is also estimated that there are approximately one million adults in the US living with some form of congenital heart disease.2 In daily practice, echocardiography is the most widely used imaging modality for diagnosis and evaluation of these patients. As medical technology has developed, this modality has continuously… View more
Author(s): Srinivas Murali Added: 3 years ago
Introduction Pulmonary arterial hypertension (PAH) is a disease affecting the pulmonary vascular endothelium of the small pulmonary vessels that causes progressive elevations in pulmonary vascular resistance, leading to right ventricular failure and death. PAH can result from a number of causes or associated risk factors. A clinical classification (Evian classification) was developed in 1993 and… View more
Author(s): Douglas P Zipes Added: 3 years ago
Atrial fibrillation (AF) is the most common sustained clinical arrhythmia. The disease has a significant socioeconomic impact, with the annual cost of treating AF estimated to be about US$3,600 per patient. Although not directly life-threatening, AF also creates a growing and significant medical impact and is associated with an increased long-term risk of stroke, heart failure, and allcause… View more
Author(s): Andrew Choi , Jonathan S Steinberg , Suneet Mittal Added: 3 years ago
Atrial fibrillation (AF) is the most frequently observed sustained cardiac arrhythmia encountered in clinical practice. Its incidence is increasing in the US.1 Numerous risk factors have been implicated in the development of AF, including non-modifiable risk factors such as age and gender, modifiable risk factors such as obesity—itself a risk factor for obstructive sleep apnea (OSA)—and smoking,… View more
Author(s): Mehmet Ali Elbey , Luis Augusto Palma Dallan , Guilherme Ferragut Attizzani Added: 3 years ago
In the article by Elbey et al. entitled “Value of MitraClip in Reducing Functional Mitral Regurgitation” (US Cardiology Review 2019;13(1):30–4. https://doi.org/10.15420/usc.2018.19.1), the following correction should be made for the second author: “Luis Augusto Palma Dalan” should be “Luis Augusto Palma Dallan”. The authors apologise for this error. View more
Author(s): Gerald V Naccarelli , Deborah L Wolbrette , Soraya Samii , et al Added: 3 years ago
Currently available antiarrhythmic drugs for the treatment of atrial fibrillation are limited in their efficacy and have potential for adverse effects, including torsade de pointes. With the aging of the population, the incidence of atrial fibrillation will double in frequency over the next 15 years. Thus, more effective and safer antiarrhythmic drugs for the treatment of atrial fibrillation are… View more
Author(s): Jason Chinitz , Dorinna D Mendoza , Raymond J Kim , et al Added: 3 years ago
Accurate detection of left ventricular (LV) thrombus affects clinical outcomes and therapeutic management, as thrombus provides a substrate for thromboembolic events and a rationale for anticoagulation. Relative risk (RR) for thrombus development is highest among subjects with systolic heart failure or myocardial infarction (MI), reflecting a link between impaired LV blood stasis, pro-coagulant… View more