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TCT 24: The TRISCEND II Trial
Author(s): Susheel Kodali Added: 1 year ago
TCT Conference 2024 - Safety and efficacy outcomes of transcatheter tricuspid valve replacement (TTVR) compared to optimal medical therapy for patients with severe tricuspid regurgitation (TR).Dr Susheel Kodali (Columbia University Medical Center, New York, US) joins us onsite at TCT Conference to discuss the findings from the TRISCEND II Trial (NCT04482062; Edwards Lifesciences).TRISCEND II is a… View more

Intervention
Device Therapies in Heart Failure
Author(s): Yoel Benarroch , Natalie Tapaskar , Amin Yehya Added: 7 months ago

Intervention

Heart Failure
LAAC Not Non-Inferior to Medical Care in High-Risk AF
Added: 1 month ago Source:  Interventional Cardiology Review Journal
For patients with atrial fibrillation (AF) at high risk for both stroke and bleeding, catheter-based left atrial appendage closure (LAAC) was not found to be non-inferior to physician-directed best medical care, according to the results of the CLOSURE-AF trial.¹MethodologyThe multicentre, randomised CLOSURE-AF trial was conducted in Germany to assess the effectiveness of LAAC compared with best… View more

Intervention

Prevention & Chronic Conditions
AHA 25: Beta-Blocker Therapy Post MI in Patients with Preserved LVEF
Author(s): Anna Meta Dyrvig Kristensen Added: 6 months ago
AHA Scientific Sessions 2025 – Dr Anna Meta Dyrvig Kristensen (Copenhagen University Hospital, Bispebjerg and Frederiksberg, DK) presents an individual patient data meta-analysis examining beta-blocker therapy after myocardial infarction in patients with preserved left ventricular ejection fraction.This comprehensive meta-analysis pooled individual patient data from five randomized controlled… View more

Heart Failure
AHA 25: CRISPR-Cas9 Gene Editing Therapy Targeting ANGPTL3
Author(s): Stephen Nicholls Added: 6 months ago
AHA Scientific Sessions 2025 - Phase 1 results show the CRISPR-Cas9 gene editing therapy is a safe treatment option targeting ANGPTL3 in patients with lipid disorders.Prof Stephen Nicholls (Monash Victorian Heart Institute, Clayton, AU) joins us to share results from a first-in-human phase 1 trial investigating a one-time infusion of CTX310, a CRISPR-Cas9 gene editing therapy, at different doses… View more

Prevention & Chronic Conditions
Novel Therapies in ATTR-CM
Author(s): Michelle Dimza , Georgia Vasilakis , Justin L Grodin Added: 6 months ago

Heart Failure
GLP-1 Medications for Patients with Moderate Peripheral Artery Disease
Author(s): Catherine Go Added: 11 months ago
Findings from a retrospective trial show GLP-1 medications for moderate peripheral artery disease (PAD) significantly decreased the risk of amputations.Dr Catherine Go (Charleston Area Medical Center, Charleston, WV, US) joins us to discuss outcomes from the largest retrospective trial evaluating the impact of GLP-1 medications for patients with moderate PAD. The study used the TriNetX database… View more

Vascular Disease and Surgery
ESC 25: Lifetime Benefits of Combination Therapy in HFpEF
Author(s): Muthiah Vaduganathan Added: 8 months ago
ESC Congress 2025 - Dr Muthiah Vaduganathan (Brigham and Women’s Hospital, Boston, US) joins us to discuss findings from a trial investigating the lifetime benefits of combination therapy for patients with HFpEF by looking at individual level data from DELIVER, FINEARTS-HF and PARAGON-HF trials.Interview Questions:1. What is the reasoning behind the trial?2. What was the study design and patient… View more

Heart Failure
Definitions and Implications of Shock Diagnosis and Therapy with Dr Frederick Welt
Author(s): Frederick Welt Added: 7 months ago
Learn about the definition and implications of a shock diagnosis and systems of care and the role of the shock team from Dr Frederick Welt (University of Utah, US).This three-part video lecture series, part of Women As One’s CLIMB® 2025 Skills Training Programme, offers case-based insights into Coronary and Mechanical Support for Cardiogenic Shock, curated by Dr Alison Duncan and Dr Frederick… View more

Intervention

MI/ACS
Navigating Digital Medical Education
Author(s): Gurleen Kaur , Saman Nematollahi , Thomas Das , et al Added: 1 year ago

Guidelines & Statements