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Author(s): Raman Dusaj , Jonathan S Reiner Added: 3 years ago
The rapid development of percutaneous coronary and peripheral vascular interventional technologies, as well as non-invasive computed tomography (CT)-based imaging systems, has led to a dramatic increase in the number of patients receiving intravenous or intra-arterial contrast media (CM). It has been estimated that more than 80 million doses (8 million litres) of contrast material are… View more
Author(s): Jennifer Franke , Horst Sievert Added: 3 years ago
After having performed angioplasty in coronary and peripheral vascular disease with excellent results, carotid angioplasty was thought to be an opportunity to simplify the treatment of carotid stenosis. Up until then there was no apparent reason to protect patients against distal embolisation. With the development of carotid angioplasty and stenting, prevention of distal embolisation of… View more
Author(s): Donald E Cutlip Added: 3 years ago
Dual anti-platelet therapy (DAPT) with aspirin and a P2Y12 inhibitor reduces recurrent ischemic events in patients with acute coronary syndrome and is recommended by guidelines for patients treated with either an early invasive or ischemia-guided strategy.1,2 For initial therapy, either clopidogrel or ticagrelor are the preferred options, with prasugrel also an option at the time of percutaneous… View more
Author(s): Raoul Bonan , Anita W Asgar Added: 3 years ago
Coronary angioplasty has revolutionized the treatment of coronary artery disease. Over the past two decades the field has seen numerous innovations in an attempt to perfect the percutaneous management of coronary atherosclerotic disease. The development of coronary stenting was a major advance in preventing elastic recoil and treating dissections following balloon angioplasty.1 Unfortunately,… View more
Author(s): Olivier F Bertrand , Tift Mann Added: 3 years ago
The highlights of the last decade in interventional cardiology have been the introduction of drug-eluting stents and an overall simplification of percutaneous coronary interventional procedures from a technological standpoint. Indeed, most interventions currently consist of either direct stenting or pre-dilatation followed by stent implantation; the use of rotational atherectomy and other niche… View more
Author(s): Thomas J Povsic Added: 3 years ago
The potential of physiological regeneration offered by stem-cell-mediated therapy has captured the imagination of both the public and the scientific community. This is especially true for the cardiovascular and nervous systems, which have long been considered terminally differentiated and post-mitotic with minimal capacity for regeneration and repair. While the ability of embryonically derived… View more
Author(s): Michael Megaly , Marwan Saad , Emmanouil S Brilakis Added: 3 years ago
Percutaneous coronary intervention (PCI) of small-vessel coronary artery disease (SVD) is challenging because of difficulties with equipment delivery and high restenosis rates. Drug-coated balloons (DCBs) are an attractive emerging PCI option for patients with SVD. Small-vessel coronary artery disease SVD was defined in the Intracoronary Stenting or Angioplasty for Restenosis Reduction in Small… View more