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Jonathan Byrne
Research Area(s) / Expertise:

Hypertension

 Job title: PhD, MB, ChB
Dr Byrne completed his undergraduate medical training in Bristol and then continued general professional medical training in the South-East of England and London. He then undertook a PhD in the academic department of Cardiology at King’s College Hospital examining molecular mechanisms underlying left ventricular hypertrophy. Following completion he undertook his specialist training in… View more
Author(s): Hillel A Steiner , Yonathan Hasin Added: 3 years ago
Sudden cardiac death (SCD) remains a public health problem of immense magnitude, afflicting an estimated 300,000 persons per year in the US.1 SCD, defined as death occurring within one hour from symptom-onset, is associated with ischemic heart disease in 80% of cases. Approximately one-third of cases are the result of an acute occlusion of an epicardial coronary artery.2 Some 50% of the mortality… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Author(s): Eric HC Yu Added: 3 years ago
Contemporary approved echo contrast agents share a common approved indication of left ventricular opacification and enhancement of endocardial border delineation for the assessment of left ventricular function in patients with technically suboptimal echocardiograms (ECGs). The use of echo contrast agents with advanced imaging technologies has resulted in the conversion of many non-diagnostic ECGs… View more

Imaging & Diagnostics
Women in ICD Trials and Studies
Author(s): Rachel Koch Warnock , Roshan D Modi , Stacy B Westerman Added: 7 months ago

Electrophysiology & Arrhythmia
Author(s): Yaser Nemshah , Alex Clavijo , Gyanendra Sharma Added: 3 years ago
Amyloidosis is a heterogenous group of disorders that develops secondary to the deposition of abnormally folded proteins, amyloid fibrils, in the extracellular space. Amyloidosis is classified according to the type of the precursor protein that results in the formation of amyloid fibrils. It can be inherited or acquired, and can involve multiple organs, including the heart. Amyloidosis that… View more

Heart Failure
EMPEROR-Preserved: Empagliflozin, Health Status, & QoL in Patients With HFpEF
Author(s): Javed Butler Added: 2 years ago
In this short interview, Dr Javed Butler (University of Mississippi Medical Center, Jackson, MS, US) discusses the findings of an analysis from the EMPEROR Preserved trial. In EMPEROR-Preserved, empagliflozin treatment was associated with reduction in the risk of the primary endpoint of CV death or HF hospitalization in patients with HFpEF. In this analysis, presented at AHA 2021, the… View more

Heart Failure

Prevention & Chronic Conditions
Author(s): Bertram Pitt Added: 3 years ago
The therapy of patients with chronic heart failure (HF) due to systolic left ventricular dysfunction (SLVD) continues to evolve. There is agreement that all patients with HF due to SLVD should be treated with an angiotensin converting enzyme inhibitor (ACE-I) and a beta-adrenergic receptor blocking agent (BB) unless contraindicated or not tolerated. The role of angiotensin receptor blocking… View more

Heart Failure
Management of Hypertension in African-Americans
Author(s): Shawna D Nesbitt Added: 3 years ago
Epidemiology Hypertension is both more common and more destructive in African-Americans than in other ethnic groups. According to the 2005–2006 National Health and Nutrition Examination Survey (NHANES) data, the current prevalence of hypertension in African-Americans is 39.1%, which is well above non-Hispanic whites at 28.5%. While awareness and treatment rates are similar between African… View more

Demographic
ACC 23: The LIVE-HCM Trial
Author(s): Rachel Lampert , Michael Ackerman , Sharlene Day Added: 1 year ago
ACC.23/WCC—We are joined onsite by principal investigator Dr Rachel Lampert (Yale School of Medicine, US), Dr Sharlene Day (Penn Medicine, US) and Dr Michael Ackerman (Mayo Clinic, US) to discuss the late-breaking findings from the LIVE-HCM Study. In this trial, investigators aimed to determine the effects of lifestyle and exercise on the well-being of patients with hypertrophic cardiomyopathy … View more

Heart Failure

Prevention & Chronic Conditions
Author(s): Otto A Smiseth , Anders Opdahl , Espen Boe , et al Added: 3 years ago
Abstract Heart failure with preserved left ventricular ejection fraction (HF-PEF), sometimes named diastolic heart failure, is a common condition most frequently seen in the elderly and is associated with arterial hypertension and left ventricular (LV) hypertrophy. Symptoms are attributed to a stiff left ventricle with compensatory elevation of filling pressure and reduced ability to increase… View more

Heart Failure