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Author(s): Raoul Bonan , Anita W Asgar Added: 3 years ago
Coronary angioplasty has revolutionized the treatment of coronary artery disease. Over the past two decades the field has seen numerous innovations in an attempt to perfect the percutaneous management of coronary atherosclerotic disease. The development of coronary stenting was a major advance in preventing elastic recoil and treating dissections following balloon angioplasty.1 Unfortunately,… View more
Author(s): Gaku Nakazawa , Aloke V Finn , Renu Virmani Added: 3 years ago
Polymer-based sirolimus (Cypher®) and paclitaxel (Taxus®) drug-eluting stents (DES) have reduced rates of restenosis and target lesion revascularization (TLR) compared with bare-metal stents (BMS) and have launched a revolution in the interventional treatment of symptomatic coronary artery disease.1,2 However, this overwhelming enthusiasm has recently been dampened by safety concerns regarding a… View more
Author(s): Gary M Ansel , Peter A Schneider Added: 3 years ago
Abstract The goal of infrapopliteal endovascular therapy is the re-establishment of straight-line flow to the foot with adequate perfusion of tissue. This treatment should be the first method in properly selected patients to relieve ischemic rest pain, heal ulcers and prevent limb loss, improving quality of life. Percutaneous angioplasty (PTA) continues to be the cornerstone of infrapopliteal… View more
Author(s): Xiaoyu Yang , Mohamed Ahmed , Donald E Cutlip Added: 3 years ago
Over the past 35 years, treatment of coronary artery disease and acute coronary syndrome has changed drastically. Balloon angioplasty offered an early mechanical solution but carried a high risk for acute complications and subsequent restenosis, mainly from recoil. The bare metal stent (BMS) improved restenosis because of recoil, but still carried a relatively high rate of restenosis because of… View more
Author(s): Peter J Fitzgerald , Martin B Leon Added: 3 years ago
An unintended consequence of the market success of drug-eluting stents has been a growing concern about their safety and safety-related costs. These devices have been so quickly and widely adopted that their market penetration already equals that of some of the most popular pharmaceutical drugs. Consequently, the absolute significance of even a low incidence of side effects becomes magnified by… View more
Author(s): Peter J Fitzgerald , Martin B Leon Added: 3 years ago
An unintended consequence of the market success of drug-eluting stents has been a growing concern about their safety and safety-related costs. These devices have been so quickly and widely adopted that their market penetration already equals that of some of the most popular pharmaceutical drugs. Consequently, the absolute significance of even a low incidence of side effects becomes magnified by… View more
Author(s): Ziad A Ali Added: 7 months ago
ESC 2023 — Dr Ziad Ali (DeMatteis St Francis, US) joins us to discuss the findings from the ILUMIEN IV clinical trial (NCT03507777). ILUMIEN IV (Abbott Medical Devices)is a prospective, single-blind clinical trial aiming to compare optical coherence tomography (OCT) to an angiography-guided stent implantation strategy. The trial investigated which method achieved a larger post-percutaneous… View more
Author(s): Donald E Cutlip Added: 3 years ago
Stent thrombosis has been recognized as a serious complication of coronary stent placement since the procedure was first reported in the 1980s.1 Subsequent aggressive peri-procedural anti-thrombotic strategies with inpatient transition to warfarin reduced the risk to about 3.5 % for subacute (30-day) stent thrombosis,2,3 a rate that would be unacceptable by current standards and did not account… View more
Author(s): Gregg Stone Added: 7 months ago
ESC 2023 — Dr Gregg Stone (Icahn School of Medicine at Mount Sinai, US) shares the findings from a real-time updated network meta-analysis comparing OCT, IVUS and Angiography guidance in percutaneous coronary intervention (PCI) procedures. The OCTOBER and ILUMIEN IV randomised trials both studied OCT-guided versus angiography-guided PCI. This analysis compared the overall effects of… View more
Author(s): Joost Daemen , Nicolas M Van Mieghem Added: 6 months ago
What's hot at TCT 2023? In this episode of View from the Thoraxcenter, Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcenter, Erasmus MC, NL) preview the late-breaking data presented at TCT 2023. With their dynamic analysis, these anticipated trials are placed in context, highlighting the real-world implications tied to the data releases. Top trials covered: 00:31 - 02:12: PARTNER 3 Low… View more