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3 years ago
The need for a patient to consult a cardiologist can be exemplified by the case a 65-year-old man who recently suffered an anterior wall myocardial infarction (MI) and who has been participating in cardiac rehabilitation, who presents with feelings of overwhelming depression and hopelessness. On three occasions since his hospitalization he has been evaluated in the local emergency department (ED)…
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3 years ago
Atrial fibrillation (AF) is a common and recurrent arrhythmia resulting in significant morbidity and mortality. Our approach to the patient with AF has changed dramatically over the past decade. We have gone from palliating patients with rate controlling medications or administering antiarrhythmic medications with potential systemic side effects and proarrhythmia, to now curing many of them with…
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3 years ago
Currently available antiarrhythmic drugs for the treatment of atrial fibrillation are limited in their efficacy and have potential for adverse effects, including torsade de pointes. With the aging of the population, the incidence of atrial fibrillation will double in frequency over the next 15 years. Thus, more effective and safer antiarrhythmic drugs for the treatment of atrial fibrillation are…
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3 years ago
Pulmonary arterial hypertension (PAH) is a progressive and debilitating disease with limited treatment options. Although some patients do well with calcium channel blockers, most ultimately need more advanced therapy, such as prostanoids. Recently, a new class of therapeutic agents has been developed to treat these patients: the endothelin receptor antagonists (ERAs). Although they are not…
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3 years ago
Acute coronary syndromes (ACS) is an umbrella term comprising a spectrum of clinical conditions ranging from unstable angina to non-ST elevation myocardial infarction and ST elevation myocardial infarction. ACS begins when an atherosclerotic plaque ruptures or erodes and a platelet-fibrin clot obstructs coronary blood flow. These critical disorders are a major cause of emergency medical care and…
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3 years ago
Pulmonary arterial hypertension (PAH) is a disorder of the pulmonary circulation in which elevated pressure in the pulmonary vascular circuit, when severe, can lead to right heart failure and eventually cause death. The last three decades have seen significant advances in our understanding of this group of disorders and, with this understanding, the development of novel therapies to assist in…
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Added:
3 years ago
Atrial fibrillation (AF) is a common and recurrent arrhythmia resulting in significant morbidity and mortality.1 Our approach to the patient with AF has changed dramatically over the past decade. We have gone from palliating patients with rate controlling medications or administering antiarrhythmic medications with potential systemic side effects and proarrhythmia,2-4 to now curing many of them…
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Added:
3 years ago
Pulmonary arterial hypertension (PAH) is a disorder of the pulmonary circulation in which elevated pressure in the pulmonary vascular circuit, when severe, can lead to right heart failure and eventually cause death. The last three decades have seen significant advances in our understanding of this group of disorders and, with this understanding, the development of novel therapies to assist in…
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Added:
3 years ago
DEFINITY® (Perflutren Lipid Microsphere Injectable Suspension, Lantheus Medical Imaging, North Billerica, MA) received approval for clinical use by the US Food and Drug Administration (FDA) in 2001 for “opacification of the left ventricular cavity and enhancement of left ventricular border delineation in patients with technically difficult echocardiograms.”1 By 2007, it was estimated that two…
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3 years ago
Contrast-induced nephropathy (CIN) represents an increasing healthcare burden and challenge as the frequency of diagnostic imaging and interventional studies increase, particularly among populations at risk of developing CIN. As the population ages, decreased renal function and increased atherosclerotic cardiovascular disease become more prevalent. Increasing levels of obesity with resultant…
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