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Author(s): Antonio Gutierrez , Sunil V Rao Added: 3 years ago
Current evidence-based therapies for ischemic heart disease include antithrombotic and antiplatelet medications that reduce the risk for ischemic outcomes such as myocardial infarction and stroke.1 Given their mechanism of action, bleeding is a risk with these agents, especially when combined with invasive procedures.2 In addition to overt bleeding, clinical trials of antithrombotic strategies… View more
Author(s): Stuart D Katz Added: 3 years ago
A recent study reported the clinical characteristics and outcomes of 43 non-edematous ambulatory patients with congestive heart failure, in whom clinical volume status was categorized by a direct measurement of blood volume by a radioisotope technique.1 Despite on-going treatment with high doses of loop diuretics and few physical signs of congestion, 65% of the subjects in this cohort were found… View more
Author(s): Maria Rosa Costanzo Added: 3 years ago
In the US, 90% of the one million annual hospitalizations for heart failure (HF) are due to volume overload.1,2 Hypervolemia contributes to HF progression and mortality. Guidelines recommend that therapy for HF patients be aimed at achieving euvolemia. Intravenous loop diuretics induce rapid diuresis that reduces lung congestion and dyspnea. However, the effectiveness of loop diuretics declines… View more
Author(s): Mitchell T Saltzberg Added: 3 years ago
Volume Overload in Heart Failure The burden of heart failure (HF) remains formidable in the US, with nearly one million annual hospital admissions and frequent outpatient visits to a variety of care providers.1 While HF outcomes have improved modestly over the past several decades, many patients still struggle to maintain a satisfactory quality of life.2 Implantable cardioverter–defibrillators… View more
Author(s): Brian Pearlman , Taffere Mihretu Added: 3 years ago
Congestive heart failure (CHF) is a rapidly growing public health problem, affecting nearly five million people in the US alone, with nearly half a million new cases annually.The prevalence of CHF is highest in the elderly; ten out of every 1,000 persons over age 65 are affected. Anemia has been considered a modifiable comorbidity in heart failure. Utilizing the World Health Organization (WHO)… View more
Author(s): Stuart W Jamieson Added: 3 years ago
Pulmonary endarterectomy for the treatment of pulmonary hypertension from chronic thromboembolic disease is an uncommonly employed surgical procedure. However, this operation provides immediate and permanent relief of the pulmonary hypertension associated with the sequelae of unresolved pulmonary thromboembolic disease. Patients are generally not referred for operation because of a lack of… View more