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Fontan-associated Liver Disease: A Practical Review
Author(s): Aleksandra Cieplucha , Werner Budts , Marc Gewillig , et al Added: 1 year ago

Heterogeneous Populations

CV Disease in Special Populations
Cardiac Transplant and Ventricular Assist in Heart Failure
Author(s): Michael T Cain , Michael S Firstenberg , Joseph C Cleveland Jr Added: 2 years ago

Heart Failure
EASD 23: Efinopegdutide in NAFLD & T2D patients
Author(s): Samuel S Engel Added: 6 months ago
EASD 2023 — In this short interview, Dr Samuel S Engel (Associate Vice President at Merck) discusses a study investigating the effectiveness and safety of efinopegdutide (MK-6024) in patients with nonalcoholic fatty liver disease and type 2 diabetes (NCT04944992).The phase IIa study randomized 145 participants (efinopegdutide, n = 72; semaglutide, n = 73). The majority (55.2%) of participants… View more

Prevention & Chronic Conditions
Author(s): Erik B Friedrich , Michael Böhm Added: 3 years ago
Chronic heart failure (CHF) is a major public health problem in industrialized societies, with an incidence approaching 10 per 1,000 population after age 65 and an age-dependent prevalence of less than 1% between ages 45 and 55, 2-5% between ages 65 and 75, and approximately 10% for patients aged 80 years or more.1-3 Thus, HF is primarily a condition of the elderly, and approximately 80% of… View more

Heart Failure
Author(s): Srinivas Murali Added: 3 years ago
Introduction Nearly five million Americans suffer from heart failure, with 550,000 new cases diagnosed with this disease each year. Heart failure is responsible for 11 million office visits and over 3.5 million hospitalizations per year in the US, with a total bill of US$23 billion spent annually on treatment. About 250,000 people in the US suffer from severe, end-stage heart failure (NYHA Class… View more

Heart Failure
Treatment of Chronic Heart Failure
Author(s): Erik B Friedrich , Michael Böhm Added: 3 years ago
Chronic heart failure (CHF) is a major public health problem in industrialized societies with an incidence approaching 10 per 1,000 population after age 65 and an age-dependent prevalence of less than 1% between ages 45-55, 2-5% between ages 65-75, and approximately 10% for patients aged 80 years or more.Thus, HF is primarily a condition of the elderly and approximately 80% of patients… View more

Heart Failure
Author(s): Marvin J Slepian Added: 3 years ago
Heart failure remains the final common pathway of all forms of heart disease. Currently, more than 20 million patients suffer with heart failure in the US and Europe combined.1 Over the past two decades, advances in medical therapeutics have made inroads in reducing mortality associated with early- and mid-stage heart failure. Unfortunately, once patients progress to advanced heart failure, i.e… View more

Vascular Disease and Surgery

Heart Failure
Author(s): Shaun R Opie , Nabil Dib Added: 3 years ago
Cardiovascular disease is the leading cause of death in Western countries. The damage that occurs during a heart attack results from the death and loss of the cells called cardiomyocytes that make up the majority of the myocardium. Medical therapy, balloon angioplasty, stent deployment, coronary artery bypass surgery, and heart transplantation are the current options available to the patient… View more

Vascular Disease and Surgery
Single-Ventricle Physiology
Author(s): Lydia Taranto , Tabitha Moe Added: 3 years ago
As we approach 50 years since the original publication describing the Fontan procedure for palliation of single-ventricle congenital heart disease, we review the basics of Fontan circulation, and the current literature concerning long-term complications. Surgical interventions have allowed children with former lethal defects to survive into adulthood and we recognize that this has led to a new… View more

Heterogeneous Populations
Author(s): Brian Pearlman , Taffere Mihretu Added: 3 years ago
Congestive heart failure (CHF) is a rapidly growing public health problem, affecting nearly five million people in the US alone, with nearly half a million new cases annually.The prevalence of CHF is highest in the elderly; ten out of every 1,000 persons over age 65 are affected. Anemia has been considered a modifiable comorbidity in heart failure. Utilizing the World Health Organization (WHO)… View more

Heart Failure