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3 years ago
Acute heart failure (AHF) is a major and growing cause of in-hospital mortality in developed countries. The prevalence of HF in an unselected population >45 years of age is estimated to be 2% and in a population >65 years of age is estimated to be 8.8%.1,2 The combination of aging of the population in many countries and improved survival after acute myocardial infarction has created rapid…
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5 months ago
AHA 2023 — Investigator, Prof Stefan James, Prof Jonas Oldgren (Uppsala University, SE) and Late-breaker host, Dr Harriette Van Spall (McMaster University, CA) discuss the findings of the DAPA-MI trial (NCT04564742).This multicenter, parallel-group, registry-based, randomized, double-blind and placebo-controlled phase 3 trial (AstraZeneca) investigated the effect of dapagliflozin 10 mg vs placebo…
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3 years ago
Understanding of the pathogenesis of congestive heart failure (CHF) has improved remarkably in recent years. However, despite better knowledge and novel pharmaceutical strategies, this disease is still one of the most brutal killers in the Western world. The pathophysiology of CHF is complex, and much of our comprehension revolves strictly around the neurohormonal and mechanical mechanisms…
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3 years ago
Congenital heart disease affects approximately 0.8% of the population.1 It is also estimated that there are approximately one million adults in the US living with some form of congenital heart disease.2 In daily practice, echocardiography is the most widely used imaging modality for diagnosis and evaluation of these patients. As medical technology has developed, this modality has continuously…
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3 years ago
The need for a patient to consult a cardiologist can be exemplified by the case a 65-year-old man who recently suffered an anterior wall myocardial infarction (MI) and who has been participating in cardiac rehabilitation, who presents with feelings of overwhelming depression and hopelessness. On three occasions since his hospitalization he has been evaluated in the local emergency department (ED)…
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6 years ago
Ambarish Pandey discusses the GWTG-HF Registry -30-Day Risk Standardized Mortality and Long-Term Survival After HF Hospitalization
Filmed by Radcliffe Cardiology on-site at theACC 2018 congress in Orlando, US
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Nikolaus Marx
Job title: Professor of Medicine
Author
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1 year ago
EASD 22 — Dr Ambarish Pandey (UT Southwestern Medical Center, US) talks about the post-hoc analyses of VERTIS CV trial.
In VERTIS CV, an SGLT2 inhibitor, ertugliflozin (Merck Sharp & Dohme LLC) reduced risk of hospitalization for heart failure compared with placebo. This post-hoc analyses investigated the efficacy of the treatment across the spectrum of ejection fractions (EF) in heart failure.
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Added:
3 years ago
The need for a patient to consult a cardiologist can be exemplified by the case a 65-year-old man who recently suffered an anterior wall myocardial infarction (MI) and who has been participating in cardiac rehabilitation, who presents with feelings of overwhelming depression and hopelessness. On three occasions since his hospitalization he has been evaluated in the local emergency department (ED)…
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Added:
3 years ago
Heart failure (HF) is a common condition and carries a considerable age-dependent all-cause mortality. As a leading cause of hospitalization in adults, ~50% of patients discharged with a diagnosis of HF are readmitted within six months, and the one-year mortality rate is 20% after an initial diagnosis is established. There is currently a chronic HF epidemic with a rapidly expanding prevalence…
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