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Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary Intervention
Author(s): Dimitrios Alexopoulos , Charalampos Varlamos , Despoina-Rafailia Benetou Added: 3 years ago
Complex percutaneous coronary intervention (PCI) usually refers to procedures that include bifurcation with two stents implanted, the treatment of three or more lesions, the implantation of three or more stents, total stent length >60 mm, or a chronic total occlusion (CTO).1 However, as there is no universal definition, other features, such as left main (LM) or proximal left anterior… View more

Intervention
Author(s): Donald E Cutlip Added: 3 years ago
Stent thrombosis has been recognized as a serious complication of coronary stent placement since the procedure was first reported in the 1980s.1 Subsequent aggressive peri-procedural anti-thrombotic strategies with inpatient transition to warfarin reduced the risk to about 3.5 % for subacute (30-day) stent thrombosis,2,3 a rate that would be unacceptable by current standards and did not account… View more

Prevention & Chronic Conditions

Intervention
Author(s): Giora Weisz Added: 3 years ago
Much has been written, but little is known, about the long-term outcomes after drug-eluting stent (DES). The introduction of DES has extended the use of stents from a passive platform for vessel wall scaffolding to an active biotechnology vehicle for local delivery of antiproliferative pharmacotherapy. Like any other therapy or medical technology, no treatment is perfect and free of potential… View more

Intervention
Author(s): Rik Rozemeijer , Wijnand P van Bezouwen , Michiel Voskuil , et al Added: 3 years ago
Dual antiplatelet therapy (DAPT) consisting of aspirin and a P2Y12 inhibitor is prescribed in the treatment of acute coronary syndrome (ACS) or following percutaneous coronary intervention (PCI) for drug-eluting stent (DES) implantation. An important misconception remains that DAPT should be prescribed to prevent stent thrombosis. Although this may seem obvious, it should be emphasized that the… View more

Intervention
Antiplatelet and Anticoagulation Therapy in ACS
Author(s): Colin T Phillips , Michael C Gavin Added: 3 years ago
Acute coronary syndrome (ACS) occurs most often when a vulnerable intracoronary plaque ruptures or erodes to expose a prothrombotic core, precipitating thrombus formation by way of platelet activation,1–3 The spectrum of ACS includes non-ST segment-elevation (NSTE) ACS, where a vulnerable plaque threatens downstream coronary perfusion manifest as an increase in symptom frequency and/or duration … View more

Prevention & Chronic Conditions

MI/ACS
Platelet Function Testing and Genotyping in Complex PCI
Author(s): Athanasios Moulias , Angeliki Papageorgiou , Dimitrios Alexopoulos Added: 2 years ago

Intervention
Dual Antiplatelet Regimens for TAVR and Cardiac CT Evaluation of Leaflets
Author(s): Mirvat Alasnag , Waqar Ahmed , Ibrahim Al-Nasser , et al Added: 2 years ago

Anticoagulation

Imaging & Diagnostics
Type and Duration of Antithrombotic Treatment in Complex PCI
Author(s): Despoina-Rafailia Benetou , Charalampos Varlamos , Christos Pappas , et al Added: 2 years ago

Anticoagulation
Author(s): Michela Faggioni , Michael C Gibson , Roxana Mehran Added: 3 years ago
The use of non-vitamin K antagonist oral anticoagulants (NVKA) has revolutionized the antithrombotic treatment of patients with atrial fibrillation (AF), finally freeing them of the inconvenience and expense of international normalized ratio measurements. However, add to the equation the presence of coronary artery disease requiring percutaneous coronary intervention (PCI) with stent placement… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Antithrombotic Therapy in Complex PCI Patients Under OAC
Author(s): Despoina-Rafailia Benetou , Panayotis K Vlachakis , Charalampos Varlamos , et al Added: 2 years ago

Anticoagulation

Intervention