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Author(s): Shamai A Grossman Added: 3 years ago
Introduction Congestive heart failure (CHF) is an imbalance in pump function in which the heart fails to maintain the circulation of blood adequately. The most severe manifestation of CHF, pulmonary edema, develops when this imbalance causes an increase in lung fluid secondary to leakage from pulmonary capillaries into the interstitium and alveoli of the lung. CHF can be categorized as forward… View more
Author(s): Nikolaus Marx Added: 3 years ago
Prof Nikolaus Marx (University Hospital Aachen, Aachen, DE) discusses the analyses of first and recurrent cardiovascular and hospitalization events in the CAROLINA trial. Questions: 1. Can you briefly remind us of the CAROLINA trial? 2. What was the rationale of this sub-analysis and what were its aims? 3. Can you tell us about the controversies regarding the cardiovascular safety of… View more
Author(s): Gregory J Dehmer , Leah White , John U Doherty Added: 3 years ago
Since the first report of a methodology to assess the appropriateness of medical technologies, the number and application of appropriate use criteria (AUC) has expanded.1 Interest in AUC occurred because of a desire to control the rising costs of medical care, especially in the area of cardiac imaging. For example, ambulatory visits in which a cardiac stress test with imaging was ordered or… View more
Author(s): Ahmad Younes , Guilherme Ferragut Attizzani , Ankur Kalra Added: 3 years ago
Transcatheter aortic valve replacement (TAVR) is a recent innovation that has transformed the care of patients with symptomatic severe aortic stenosis. It has emerged as an alternative for surgical aortic valve replacement (SAVR) in prohibitive-, high-risk, and more recently, intermediate-risk surgical patients. More than 200,000 TAVRs have been performed in 65 countries around the world.1 As… View more
Author(s): Randal J Thomas Added: 3 years ago
The need for a patient to consult a cardiologist can be exemplified by the case a 65-year-old man who recently suffered an anterior wall myocardial infarction (MI) and who has been participating in cardiac rehabilitation, who presents with feelings of overwhelming depression and hopelessness. On three occasions since his hospitalization he has been evaluated in the local emergency department (ED)… View more
Author(s): Nader Moazami Added: 3 years ago
Among the many advances in medical therapy, the last decade has certainly witnessed the emergence of mechanical assist therapy from a dream to a tangible reality. Advances in device design, surgical techniques, and post-operative management have clearly and firmly established these devices as a critical option available for the treatment a challenging group of patients with heart failure. This… View more
Author(s): Rajalakshmi Santhanakrishnan Added: 3 years ago
Heart failure (HF) is a major health problem and about 6 million adults are affected in the US alone, at a cost of approximately $20 billion per year.1 Despite the availability of new treatment strategies, the incidence, number of hospitalizations and mortality associated with HF remains a big health burden.1 In addition to increasing age, the factors that contribute to poor prognosis for people… View more
Author(s): Brian Bergmark Added: 1 week ago
ACC.24 — Dr Brian Bergmark (Brigham and Women's Hospital, Harvard Medical School, US) joins us in this interview to discuss the findings of a study into olezarsen, previously known as AKCEA-APOCIII-LRx, in patients with hypertriglyceridemia and atherosclerotic cardiovascular disease (ASCVD), with or without severe hypertriglyceridemia (NCT05355402).This multicenter, randomized, double-blind study… View more
Author(s): Steven R Sigman Added: 3 years ago
Although less common than other forms of cardiomyopathy, cardiac sarcoidosis (CS), both as part of a systemic process and in its isolated form, is an important, and increasingly recognized disorder. This is felt to be due, in part, to advances in cardiac imaging and heightened awareness of the disorder.1,2 CS is associated with high rates of morbidity and mortality, including sudden cardiac death… View more
Author(s): Bill D Gogas , Jun-Jie Zhang , Shao-Liang Chen Added: 3 years ago
The current generation of drug-eluting stents (DES) that are clinically available in the US represent significant advancements compared to angioplasty, bare metal stents, and the first generation of DES. The Xience everolimus-eluting stents (Abbott Vascular), Promus everolimus-eluting stents (Boston Scientific) and Resolute zotarolimus-eluting stents (Medtronic) demonstrate the optimal balance of… View more