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Author(s): Gurushankar Govindarajan , James R Sowers , Craig S Stump Added: 3 years ago
There has been an increase in the prevalence of diabetes mellitus over the past 40 years, both in the US and worldwide. The worldwide prevalence of diabetes in 2000 was approximately 2.8% and is estimated to grow to 4.4% by 2030. This translates to a projected rise of diabetes from 171 million in 2000 to well over 350 million in 2030. The epidemic of diabetes will continue to rise as there is… View more

Prevention & Chronic Conditions
Author(s): Frans J Th Wackers , Janice A Davey Added: 3 years ago
Diabetes mellitus is an important risk factor for cardiovascular disease. Moreover, cardiovascular diseases are the leading causes for morbidity and mortality in patients with type 2 diabetes mellitus. The high mortality rate is partly due to the diabetic state per se, above and beyond the clustering of other risk factors such as hypertension, dyslipidemia, and obesity. Over the last decade, the… View more

Prevention & Chronic Conditions
Author(s): Frans J Th Wackers , Janice A Davey Added: 3 years ago
Diabetes mellitus is an important risk factor for cardiovascular disease. Moreover, cardiovascular diseases are the leading causes for morbidity and mortality in patients with type 2 diabetes mellitus. The high mortality rate is partly due to the diabetic state per se, above and beyond the clustering of other risk factors such as hypertension, dyslipidemia, and obesity. Over the last decade, the… View more

Prevention & Chronic Conditions
Author(s): Donald E Cutlip Added: 3 years ago
Abstract Coronary artery disease in patients with diabetes is frequently a diffuse process with multivessel involvement and is associated with increased risk for myocardial infarction and death. The role of percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG) in patients with diabetes and multivessel disease who require revascularization has been debated and… View more

Prevention & Chronic Conditions
Author(s): Erik M Kelly , Donald E Cutlip Added: 3 years ago
Diabetes mellitus is one of the most common chronic diseases, affecting >30 million people in the US and 422 million worldwide.1,2 Alarmingly, both the incidence and prevalence of type 2 diabetes have doubled in the US since 1990.3 This is driven by an aging population, obesity, physical inactivity, and prolonged survival in those with diabetes, among other factors. It is estimated that… View more

Prevention & Chronic Conditions

MI/ACS
ADA 2020: Findings from EMPA-REG OUTCOME trial
Author(s): Muthiah Vaduganathan Added: 3 years ago
In this video, Dr Muthiah Vaduganathan (Brigham and Women's Hospital, Boston, US) shares the findings from the EMPA-REG OUTCOME trial. The goal of the trial was to assess the cardiovascular (CV) safety of empagliflozin, a sodium–glucose cotransporter 2 (SGLT-2) inhibitor, in patients with type 2 diabetes mellitus (T2DM) at high risk for CV events. Questions: 1. What is the background of… View more

Prevention & Chronic Conditions
ACC 2018: Canagliflozin & heart failure in type 2 diabetes
Author(s): Gemma Figtree Added: 6 years ago
Gemma Figtree discusses the CANVAS trial - canagliflozin and heart failure in type 2 diabetes mellitus. Filmed by Radcliffe Cardiology on-site at the American College of Cardiology congress 2018 in Orlando, USA. View more

Heart Failure

Prevention & Chronic Conditions
Author(s): Hou Tee Lu , Rusli Bin Nordin , Aizai Azan Bin Abdul Rahim Added: 3 years ago
Heart failure (HF) is a global public health problem, affecting an estimated 26 million people worldwide and resulting in more than 1 million hospitalizations annually in the US and Europe.1 This HF pandemic is also evident in Asia and other parts of the world.2–4 Although the outcomes for HF patients have improved with the discovery of multiple evidence-based drug and device therapies,… View more

Demographic
Author(s): Theodore Mazzone Added: 3 years ago
Patients with type 2 diabetes mellitus (DM) have a marked increase in the risk of myocardial infarction (MI), and a substantially worse prognosis after MI compared with patients without diabetes.1–3 In recent years, it has become apparent that optimal control of blood pressure and low-density lipoprotein cholesterol (LDL-C) level can substantially reduce excess cardiovascular risk in patients… View more

Prevention & Chronic Conditions

MI/ACS
Dyslipidemia: Current Therapies and Guidelines for Treatment
Author(s): Edward T Carreras , Donna M Polk Added: 3 years ago
Cardiovascular disease affects more than one-third of American adults and is the leading cause of mortality in the United States and worldwide.1 Only 4.5 % of those over the age of 20 meet the ideal levels of the seven metrics of cardiovascular health including cholesterol levels.1 Of modifiable risk factors, including smoking, hypertension, diabetes, and obesity, dyslipidemia has been shown to… View more

Prevention & Chronic Conditions