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Author(s): Colin M Barker , Michael J Reardon Added: 3 years ago
Aortic stenosis (AS) has a long latent period and then rapid progression with high mortality once symptoms appear.1 The absence of an effective medical therapy for symptomatic severe AS led to a class I indication for aortic valve replacement (AVR) in both the US and European guidelines.2,3 Unfortunately, a study by Bach et al. in 2009 found that up to half of patients with symptomatic severe AS… View more
Author(s): Deepak L Bhatt , Anna Meta Dyrvig Kristensen , Manan Pareek , et al Added: 3 years ago
Hypertension is an important contributor to global morbidity and mortality and is a major burden on healthcare systems.1,2 More than 20% of the world’s population has high blood pressure when defined by conventional criteria: systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg.3,4 Even with therapeutic lifestyle and pharmacological measures, blood pressure remains poorly… View more
Author(s): Karthiek R Narala , Thomas A LaLonde , Sohail Hassan , et al Added: 3 years ago
Chronic kidney disease (CKD) affects approximately 26 million people in the US.1 CKD is considered a coronary risk equivalent and also a risk factor for progression of cardiovascular disease (CVD).2 Cardiovascular death rates are 10–30 times higher in dialysis patients than in the general population.3 This increase in CKD patients is multifactorial and is now mainly considered via two pathways:… View more
Author(s): Michael Megaly , Marwan Saad , Emmanouil S Brilakis Added: 3 years ago
Percutaneous coronary intervention (PCI) of small-vessel coronary artery disease (SVD) is challenging because of difficulties with equipment delivery and high restenosis rates. Drug-coated balloons (DCBs) are an attractive emerging PCI option for patients with SVD. Small-vessel coronary artery disease SVD was defined in the Intracoronary Stenting or Angioplasty for Restenosis Reduction in Small… View more
Author(s): Giovanni Maria Vescovo , Carlo Zivelonghi , Benjamin Scott , et al Added: 3 years ago
Coronary chronic total occlusion (CTO), defined as complete occlusion of a coronary artery for at least 3 months with thrombolysis in myocardial infarction (TIMI) grade 0 flow, represents one of the most complex situations in the field of interventional cardiology.1 Despite an incidence of CTO in patients with stable coronary artery disease (CAD) undergoing coronary angiography of 18–46%, the… View more