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Author(s): Jorge Silva Enciso , Eric Adler , Barry H Greenberg Added: 3 years ago
Advanced heart failure (AHF) affects approximately 5–10 % of the current 6.6 million people living with heart failure, having a higher incidence in those above 65 years of age.1 The presence of the disease is associated with 50–80 % mortality at 1 year, indicating the need for innovative therapies to manage the burden of this disease. Heart transplantation is the gold standard for AHF, although… View more

Heart Failure
Cardiac Transplant and Ventricular Assist in Heart Failure
Author(s): Michael T Cain , Michael S Firstenberg , Joseph C Cleveland Jr Added: 2 years ago

Heart Failure
Author(s): James N Kirkpatrick , Susan E Wiegers , J Eduardo Rame , et al Added: 3 years ago
There are at least five million patients with heart failure (HF) in the US, 5% of whom are considered end-stage.1 Mechanical circulatory support (MCS) in the form of ventricular assist devices (VADs) is becoming an increasingly important option for these patients. Previously reserved for rescuing patients in the throes of refractory cardiogenic shock, MCS is now a mainstay of end-stage heart… View more

Imaging & Diagnostics
Author(s): Kiran K Khush , Sharon A Hunt Added: 3 years ago
The field of heart transplantation has evolved tremendously since Alexis Carrel first explanted a canine heart and anastomosed it to the carotid artery and jugular vein of a recipient dog in 1905.1 In 1960, Norman Shumway and Richard Lower at Stanford described a technique for orthotopic canine heart transplantation and demonstrated adequate physiologic function of the denervated heart.2 Their… View more

Vascular Disease and Surgery
Author(s): Marvin J Slepian Added: 3 years ago
Heart failure remains the final common pathway of all forms of heart disease. Currently, more than 20 million patients suffer with heart failure in the US and Europe combined.1 Over the past two decades, advances in medical therapeutics have made inroads in reducing mortality associated with early- and mid-stage heart failure. Unfortunately, once patients progress to advanced heart failure, i.e… View more

Vascular Disease and Surgery

Heart Failure
Author(s): James R Revenaugh Added: 3 years ago
This article examines the initial results of the authorÔÇÖs experience to date with percutaneous left ventricular assist (LVA) support of patients in cardiogenic shock, and for temporary left heart support in the setting of high-risk percutaneous intervention. Despite evolving procedural methods, 16 of 18 patients in this study survived to hospital discharge. Intraprocedural complications were… View more

Intervention
Author(s): Jack Copeland Added: 3 years ago
Mechanical circulatory support (MCS) devices are changing heart failure therapy. A spectrum of devices have become essential to the management of a variety of heart failure scenarios and, in the next few decades, this spectrum will expand and improve thousands of lives each year. The field has grown slowly and at considerable cost over the past 50 years but is now moving rapidly. Devices as small… View more

Vascular Disease and Surgery

Heart Failure
The Role of Hemodynamic Support in High-risk Percutaneous Coronary Intervention
Author(s): Charles Simonton , Craig Thompson , Jason R Wollmuth , et al Added: 3 years ago
Coronary artery disease (CAD) is a leading cause of morbidity and mortality globally, despite advances in medical and preventive therapy. It is estimated that 18.2 million adults in the US have CAD, with 720,000 Americans projected to have a first hospitalization for MI or CAD death this year.1 Treatment of patients with symptomatic CAD includes guideline-directed medical therapy and coronary… View more

Intervention
Author(s): Ahmed M Alabbady , Ahmed S Abdul-Al , Kimberly A Skelding Added: 3 years ago
The introduction of percutaneous coronary angioplasty in 1977 by Dr Andreas Grüntzig1 was one of the most remarkable achievements in the cardiology realm, opening the door to numerous advancements in percutaneous coronary interventions (PCIs). Due to advances in PCI techniques over the past four decades, catheters along with four generations of coronary stents have dramatically changed the… View more

Intervention
Author(s): Alexandra Gonçalves , Carla Sousa , José Alberto de Agustín , et al Added: 3 years ago
Valvular disease is the most prevalent structural heart disease among adults and its burden is growing along with the increase in life expectancy.1 Mitral regurgitation (MR) is the second most frequent valvular disease, after aortic stenosis. Its natural history is very variable and highly dependent on the presence of symptoms. However, even in asymptomatic patients, the prognosis of severe MR is… View more

Vascular Disease and Surgery

Imaging & Diagnostics