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Author(s): Raif Tawakol Added: 3 years ago
Many patients on statin therapy understandably develop a false sense of security. They enjoy a lowered level of low-desity lipoprotein (LDL) and a risk reduction of some 35%. However, two out of three patients develop a myocardial infarction (MI) while on a statin therapy. Statins often do not increase HDL levels to any substantial degree (except for Rosuvastatin, which increases high-density… View more

Prevention & Chronic Conditions
Author(s): Raif Tawakol Added: 3 years ago
Many patients on statin therapy understandably develop a false sense of security. They enjoy a lowered level of low-desity lipoprotein (LDL) and a risk reduction of some 35%. However, two out of three patients develop a myocardial infarction (MI) while on a statin therapy. Statins often do not increase HDL levels to any substantial degree (except for Rosuvastatin, which increases high-density… View more

Prevention & Chronic Conditions
Author(s): Leo Buckley , Ahmed Aldemerdash Added: 3 years ago
Cardiovascular disease is the leading cause of death in the US.1,2 Although advances in the prevention and treatment of cardiovascular disease have contributed to a decline in mortality rates, this favorable trend has slowed over the past several years.3 Recently, however, a revival of cardiovascular drug development has introduced new treatment options to the market, with several promising… View more

Prevention & Chronic Conditions
Author(s): Marc P Allard-Ratick , Pratik Sandesara , Arshed A Quyyumi , et al Added: 3 years ago
Historically, HDL cholesterol (HDL-C) has been inversely associated with adfverse cardiovascular outcomes such as MI, stroke, and cardiovascular death.1–3 This led to widespread belief that HDL-C, in addition to LDL cholesterol (LDL-C), was a modifiable risk factor for cardiovascular disease. However, efforts to increase HDL-C in high-risk patients with well-controlled LDL-C values have not… View more

Prevention & Chronic Conditions
Author(s): Mohit Gupta , Borut Jug , Matthew J Budoff Added: 3 years ago
Diabetes and Cardiovascular Disease Diabetes has long been recognized as a major risk factor for cardiovascular disease and is widely regarded as a ‘coronary disease equivalent,’1,2 as diabetes and established coronary heart disease indicate a similar absolute risk for cardiovascular death in both men and women.3–5 Cardiovascular complications of diabetes have traditionally been regarded as… View more

Prevention & Chronic Conditions
Author(s): Sergio Fazio Added: 3 years ago
The wide utilization of anti-cholesterol agents, such as the statins, has created confusion among patients and clinicians about what to do when the lipid problem is one of triglycerides and high-density lipoprotein (HDL), rather than one of low density lipoprotein (LDL). Although most patients with diabetes have a dyslipidemia characterized by high triglycerides and low HDL (atherogenic… View more

Prevention & Chronic Conditions
Author(s): Sergio Fazio Added: 3 years ago
Introduction The main controversy in the area of lipid management today is related to the usefulness of 'non-statin’ agents to maximize cardiovascular risk reduction in particular patient types, such as those with diabetes and metabolic syndrome. Fibrate drugs, such as gemfibrozil (Lopid) and fenofibrate (TriCor), are undoubtedly the best tools to address the condition characterized by high… View more

Prevention & Chronic Conditions
Author(s): Krisztina M Zsebo , Brian E Jaski Added: 3 years ago
Despite important therapeutic improvements in pharmacological and device therapies, the prognosis for patients with advanced cardiovascular disease is poor, even with optimal pharmacological and device management. Heart failure continues to be a major cause of morbidity and mortality in the US. It is the leading medical cause of hospitalization and is expected to result in an estimated direct and… View more

Heart Failure
Author(s): David Morrow Added: 3 years ago
Risk stratification of patients with an acute coronary syndrome (ACS) starts on presentation and is a continuous process to predict those who are at high risk for further ischemic events or adverse outcomes. Among patients with non-ST-elevation myocardial infarction (NSTEMI), risk stratification begins with initial assessment to detect patients at immediate high risk. Subsequent evaluation is… View more

MI/ACS
Author(s): Stuart W Zarich Added: 3 years ago
The clustering of cardiovascular (CV) risk factors associated with insulin is known as 'syndrome XÔÇÖ, the 'deadly quartetÔÇÖ, and 'dysmetabolic syndromeÔÇÖ among others. In addition to the clustering of obesity, hypertension (HTN), glucose intolerance, high triglycerides, and low high-density lipoprotein (HDL), other metabolic abnormalities have been associated with this syndrome, including… View more

Prevention & Chronic Conditions