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3 years ago
Cardiovascular disease (CVD) is the leading cause of death in both men and women, yet the extent of the problem in women is frequently underestimated and, compared with men, women are less likely to be offered interventions, are less likely to be represented in clinical trials and have a worse prognosis. This article aims to examine the extent of the problem of CVD in women, summarise the…
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3 years ago
Cardiovascular disease (CVD) is the leading cause of death and disability in American women. Since 1984, more women have died of cardiovascular disease than men. More than 200,000 of these deaths are due to coronary heart disease.1 In two-thirds of these women, sudden death was the presenting symptom and studies2 show that 90% of them had at least one of the modifiable risk factors (e.g…
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3 years ago
The US has the highest maternal mortality rate in the developed world, at an estimated 26.4 deaths per 100,000 live births. This rate is rising, although it is falling in other wealthy nations.1 Cardiovascular disease is a leading cause of maternal death, so cardiologists need to build on their knowledge and enhance their proficiency on the management of cardiovascular disease during pregnancy.2
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3 years ago
In late December 2019, an outbreak of an unknown disease called a pneumonia of uncertain cause occurred in Wuhan, Hubei Province, China.1 Over the next few days, several independent laboratories identified the causative agent as a novel coronavirus.2–4 The WHO has temporarily named this virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the related infectious disease…
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3 years ago
Epidemiological studies indicate an inverse relationship between the consumption of fruits and vegetables, rich in polyphenolic compounds, and cardiovascular disease.2 These findings offer an explanation for the 'French Paradox™, the paradoxical observation that the French have a lower incidence of cardiovascular disease than Americans, despite having similar cardiac risk factors.3 The French…
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3 years ago
Dr Jean-Claude Tardif (Montreal Heart Institute, Montreal, CA) discusses the effects of Apolipoprotein C-III (ApoC-III) reduction in cardiovascular (CV) disease. The administration of APOCIII-LRX in patients with hypertriglyceridemia and high CV risk was associated with inhibition of ApoC-III and lower levels of triglycerides.
Questions:
1. What is the background of this study?
2. What was the…
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3 years ago
Cardiovascular disease is the leading cause of death in the US.1,2 Although advances in the prevention and treatment of cardiovascular disease have contributed to a decline in mortality rates, this favorable trend has slowed over the past several years.3 Recently, however, a revival of cardiovascular drug development has introduced new treatment options to the market, with several promising…
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3 years ago
Cardiovascular disease is both the dominant health problem and the major cause of mortality for adult women in the US, claiming the lives of nearly 500,000 women annually. The staggering impact is that a US woman dies from cardiovascular disease almost every minute.
Although cardiovascular disease has traditionally been perceived to be a problem predominantly of men, since 1984, more US women…
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Diversity in Cardiovascular Disease
Video Series
Added:
3 years ago
Abstract
Recently, we had the opportunity to review the progress that has been made in the field of cardiovascular disease over the past century in The FASEB Journal and, based on those thoughts, in this article we predict what may transpire in this 'century of biology'. Although it is true that 'the best way to predict the future is to invent it', we gaze through the prism of modern…
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