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Treatment of Fetal and Neonatal Arrhythmias
Author(s): Ali N Zaidi , Pamela S Ro Added: 3 years ago
Fetal and neonatal arrhythmias are diverse in type and severity. They include both tachycardias and bradycardias.1 The innate physiological properties of the fetal and neonatal myocardium make it more vulnerable to these high or low ventricular rates. Irregularities of fetal and neonatal cardiac rhythm commonly occur and rarely have serious consequences;however, it is important to realize that… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
TWILIGHT: A Randomized Trial of Ticagrelor Monotherapy Versus Ticagrelor Plus Aspirin Beginning at 3 Months in High-risk Patients Undergoing Percutaneous Coronary Intervention
Author(s): Johny Nicolas , Usman Baber , Roxana Mehran Added: 3 years ago
Seminal clinical trials conducted in the balloon angioplasty and bare metal stent era established the superiority of dual antiplatelet therapy (DAPT) as compared with aspirin monotherapy or anticoagulation with respect to the prevention of thrombotic events.1,2 Other studies found that the benefits of DAPT are durable for at least 1 year and extend to patients with acute coronary syndromes.3–5… View more

Anticoagulation
Vascular Access Management of Complex High Risk Interventional Procedures
Author(s): Jimmy Kerrigan , Timir K Paul , Jay Patel , et al Added: 6 months ago

Intervention
Percutaneous Coronary Intervention for Chronic Total Occlusion
Author(s): Giovanni Maria Vescovo , Carlo Zivelonghi , Benjamin Scott , et al Added: 3 years ago
Coronary chronic total occlusion (CTO), defined as complete occlusion of a coronary artery for at least 3 months with thrombolysis in myocardial infarction (TIMI) grade 0 flow, represents one of the most complex situations in the field of interventional cardiology.1 Despite an incidence of CTO in patients with stable coronary artery disease (CAD) undergoing coronary angiography of 18–46%, the… View more

Intervention
Author(s): Marvin J Slepian Added: 3 years ago
Heart failure remains the final common pathway of all forms of heart disease. Currently, more than 20 million patients suffer with heart failure in the US and Europe combined.1 Over the past two decades, advances in medical therapeutics have made inroads in reducing mortality associated with early- and mid-stage heart failure. Unfortunately, once patients progress to advanced heart failure, i.e… View more

Vascular Disease and Surgery

Heart Failure
Current Thinking in Acute Congestive Heart Failure and Pulmonary Edema
Author(s): Shamai A Grossman Added: 3 years ago
Introduction Congestive heart failure (CHF) is an imbalance in pump function in which the heart fails to maintain the circulation of blood adequately. The most severe manifestation of CHF, pulmonary edema, develops when this imbalance causes an increase in lung fluid secondary to leakage from pulmonary capillaries into the interstitium and alveoli of the lung. CHF can be categorized as forward… View more

Heart Failure

Prevention & Chronic Conditions
Who should be referred for TAVR
Author(s): Colin M Barker , Michael J Reardon Added: 3 years ago
Aortic stenosis (AS) has a long latent period and then rapid progression with high mortality once symptoms appear.1 The absence of an effective medical therapy for symptomatic severe AS led to a class I indication for aortic valve replacement (AVR) in both the US and European guidelines.2,3 Unfortunately, a study by Bach et al. in 2009 found that up to half of patients with symptomatic severe AS… View more

Vascular Disease and Surgery

Intervention
Author(s): Maria Rosa Costanzo Added: 3 years ago
In the US, 90% of the one million annual hospitalizations for heart failure (HF) are due to volume overload.1,2 Hypervolemia contributes to HF progression and mortality. Guidelines recommend that therapy for HF patients be aimed at achieving euvolemia. Intravenous loop diuretics induce rapid diuresis that reduces lung congestion and dyspnea. However, the effectiveness of loop diuretics declines… View more

Heart Failure
Author(s): Jorge Silva Enciso , Eric Adler , Barry H Greenberg Added: 3 years ago
Advanced heart failure (AHF) affects approximately 5–10 % of the current 6.6 million people living with heart failure, having a higher incidence in those above 65 years of age.1 The presence of the disease is associated with 50–80 % mortality at 1 year, indicating the need for innovative therapies to manage the burden of this disease. Heart transplantation is the gold standard for AHF, although… View more

Heart Failure
Management of Cardiovascular Disease During Pregnancy
Author(s): Nandita S Scott Added: 3 years ago
The US has the highest maternal mortality rate in the developed world, at an estimated 26.4 deaths per 100,000 live births. This rate is rising, although it is falling in other wealthy nations.1 Cardiovascular disease is a leading cause of maternal death, so cardiologists need to build on their knowledge and enhance their proficiency on the management of cardiovascular disease during pregnancy.2 … View more

Demographic

Heterogeneous Populations