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St. Jude Medical develops medical technology and services that focus on putting more control into the hands of those who treat cardiac, neurological and chronic pain patients worldwide. The company is dedicated to advancing the practice of medicine by reducing risk wherever possible and contributing to successful outcomes for every patient. Headquartered in St. Paul, Minn., St. Jude Medical… View more
Frits Prinzen
Job title: Professor of Physiology
Personal History Prof Frits W. Prinzen was born July 2nd, 1954, in Hilversum, the Netherlands. He is a world expert in pacing therapies, both for bradycardia and heart failure.1 His other interests include running, skating, biking and hiking.5 Academic History In 1978, Prof Prinzen earned his Master's degree in Medical Biology from Utrecht University. In 1982, he received his PhD… View more
Author(s): Jagmeet P Singh Added: 3 years ago
Cardiac resynchronization therapy (CRT) has achieved widespread approval as a safe and efficient therapeutic strategy for medically refractory congestive heart failure (CHF). The standard indications for CRT include patients with advanced heart failure and evidence of systolic dysfunction (ejection fraction [EF] ≤35%), conduction tissue disease (QRS duration ≥120ms), and marked cardiac symptoms … View more

Heart Failure

Electrophysiology & Arrhythmia
Added: 3 years ago
One-third of Patients Not Receiving Defibrillation in Time Patients are not receiving defibrillation soon enough after initial cardiac arrest, according to a study published in the New England Journal of Medicine. Delay in defibrillation—defined as coming after more than two minutes—is associated with a lower survival rate and lower likelihood of return to spontaneous circulation following… View more

Standards & Guidelines

MI/ACS
Author(s): Nico A Blom Added: 3 years ago
Cardiac resynchronization therapy (CRT) using biventricular pacing has been proven to be effective in adult patients with left ventricular (LV) systolic dysfunction and QRS prolongation. In this group of patients, CRT improves exercise tolerance, symptoms of heart failure and all-cause mortality.1 In addition, there is growing evidence that inter- and intra-ventricular dyssynchrony induced by… View more

Electrophysiology & Arrhythmia
Author(s): Alan J Bank , Kevin V Burns , Ryan M Gage Added: 3 years ago
Cardiac resynchronization therapy (CRT) is a well-accepted and proven therapy for the treatment of patients with advanced heart failure (HF), significant left ventricular (LV) systolic dysfunction, and a wide QRS complex on electrocardiogram (ECG). In this patient population, large multicenter studies have demonstrated that CRT improves symptoms of HF, exercise capacity, LV size and systolic… View more

Imaging & Diagnostics

Heart Failure
Author(s): Tasneem Z Naqvi Added: 3 years ago
Congestive heart failure (CHF) is the number one hospital discharge diagnosis for older adults and the leading cause of hospital readmissions, reflecting poor quality of life for patients and increased healthcare resource use, and is the cause of 300,000 deaths annually.1 Cardiac resynchronization therapy (CRT) has become a new effective treatment modality in those with drug-resistant advanced… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Ernesto E Salcedo Added: 3 years ago
A working definition of Heart Failure (HF) was recently conceptualized by the Heart Failure Society of America as: "a syndrome caused by cardiac dysfunction, generally resulting from myocardial muscle dysfunction or loss and characterized by LV dilation or hypertrophy. Whether the dysfunction is primarily systolic or diastolic or mixed, it leads to neurohormonal and circulatory abnormalities,… View more

Imaging & Diagnostics

Heart Failure
Author(s): Soraya M Samii , Javier E Banchs Added: 3 years ago
Abstract The concept of using an implantable device to manage arrhythmias and heart failure started over 50 years ago. Since then, we have seen these devices improve patient outcomes from bradyarrhythmias, atrial fibrillation, ventricular arrhythmias, and heart failure. These devices are now standard of care in the management of patients and include pacemakers, implantable cardioverter… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Dante J Graves , Rick W Meece Added: 3 years ago
Despite significant improvements for earlier detection of and medical therapies for heart failure, a recent American Heart Association (AHA) study stated that the actual incidence of heart failure has not declined. Of interest is the fact that the AHA found hypertension precedes development of heart failure in 91% of cases. The increasing prevalence of these combined disease states escalates the… View more

Imaging & Diagnostics

Heart Failure