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Author(s): Morton J Kern , Katherine M Yu Added: 3 years ago
Coronary artery disease (CAD), the most common cause of morbidity and mortality in the US, is frequently identified by coronary angiography. Decisions for treatment are often based on angiography alone, absent other clinical indicators for intervention. However, by angiography alone, conventional wisdom has suggested that a coronary stenosis is significant if there is at least a 50 % diameter… View more

Prevention & Chronic Conditions
TCT 22: PARTNER 3: SAPIEN 3 Valve For Failed Aortic Bioprosthetic Valves
Author(s): Santiago Garcia Added: 1 year ago
TCT 22 - Dr Santiago Garcia (Minneapolis Heart Institute at Abbott Northwestern Hospital, MN, US) joins us to discuss the findings of a substudy of the PARTNER 3 Trial which aimed to evaluate the safety and efficacy of Edwards' SAPIEN 3 Ultra transcatheter heart valve in aortic stenosis patients with a failing bioprosthetic valve. In this study, 125 patients received TAVR using the Sapien 3… View more

Intervention
Johnathan Yap
Research Area(s) / Expertise:

Coronary Interventions

Coronary Physiology

 Job title: Consultant Cardiologist
Clinical Associate Professor Jonathan Yap is a Consultant with the Department of Cardiology at NHCS. His subspeciality interest is in interventional cardiology, pulmonary hypertension and structural heart disease including transcatheter aortic valve interventions (TAVI) for aortic stenosis. He spent a year in the United States performing his advanced fellowship in structural heart interventions… View more
Cardio-oncology A-Z: Radiation Induced Heart Disease With Dr Joshua Mitchell
Author(s): Joshua Mitchell Added: 1 year ago
In this video we asked, Dr Joshua Mitchell, Assistant Professor of Medicine at Washington University School of Medicine and the Director of our Cardio-Oncology Centre Of Excellence, to summarise the topic of radiation induced heart disease. Dr Mitchell's clinical interests include cardiotoxicity from cancer therapy and cancer survivorship. Discussion Points: 1. Types of Radiation Induced Heart… View more

CV Disease in Special Populations
Clinical Trial Perspective: Cost-effectiveness of Transcatheter Mitral Valve Repair Versus Medical Therapy in Patients with Heart Failure and Secondary Mitral Regurgitation. Results From the COAPT Trial
Author(s): Suzanne J Baron Added: 3 years ago
In the wake of transcatheter aortic valve replacement revolutionizing the treatment of aortic stenosis, sizeable interest has arisen in the development of percutaneous technologies to treat patients with mitral valve disease. Thus, when a percutaneous method of edge-to-edge mitral valve repair (TMVr) using the MitraClip device (Abbott Vascular) was introduced, this device was met with… View more

Heart Failure

Intervention
Author(s): Peter A McCullough Added: 3 years ago
Heart failure (HF) is a common condition and carries a considerable age-dependent all-cause mortality.1 As a leading cause of hospitalization in adults, ~50% of patients discharged with a diagnosis of HF are readmitted within six months, and the one-year mortality rate is 20% after an initial diagnosis is established. There is currently a chronic HF epidemic with a rapidly expanding prevalence… View more

Prevention & Chronic Conditions
TCT 23: WATCH-TAVR: WATCHMAN for Patients with AF Undergoing TAVR
Author(s): Samir R Kapadia Added: 5 months ago
TCT 23 - We are joined by Dr Samir Kapadia (Cleveland Clinic, Cleveland, OH) to discuss the findings of the WATCH-TAVR Trial (NCT03173534). WATCH-TAVR aimed to evaluate the safety and effectiveness of left atrial appendage occlusion with the WATCHMAN device to prevent stroke and bleeding in patients with atrial fibrillation (AF) who are undergoing transcatheter aortic valve replacement (TAVR)… View more

Electrophysiology & Arrhythmia

Intervention
Between a Rock and a Hard Place: How to Use Antithrombotics in Patients Undergoing Transcatheter Aortic Valve Replacement
Author(s): Mathew R Williams , Kelsey Grossman , Homam Ibrahim Added: 3 years ago
Transcatheter aortic valve replacement (TAVR) has become the preferred method for management of severe aortic stenosis in patients who are at high and intermediate surgical risk. Short-term data have been presented from two studies comparing TAVR versus surgical aortic valve replacement (SAVR) in low surgical risk patients. The Placement of Aortic Transcatheter Valves 3 (PARTNER 3) trial compared… View more

Anticoagulation
PARTNER 3: TAVR is Cost Effective Compared with SAVR for Low-Risk Patients
Author(s): David J Cohen Added: 2 years ago
Dr David J Cohen (St Francis Hospital, Roslyn, NY, US) discusses the findings from PARTNER 3 Economic Study. The study, presented first at TCT 2021, showed that for patients with severe AS and low surgical risk, TF-TAVR with the SAPIEN 3 valve is cost-saving compared with SAVR at 2-year follow-up. Discussion Points Importance of the Study Used Data Complexities in Relation to the Costs of… View more

Intervention
Repeat TAVR Outcomes: Promising Results for Selected Patients with Failed TAVR
Author(s): Raj Makkar Added: 6 months ago
In this insightful interview, investigator, Prof Raj R Makkar(Cedars-Sinai Heart Institute, US) joins us to discuss the outcomes of repeat transcatheter aortic valve replacement with balloon-expandable valves. Prof Makkar and his team used the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry to address a series of questions regarding the safety… View more

Intervention