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Author(s): Ross Arena , Carl J Lavie Added: 3 years ago
Excess body weight in the form of adipose tissue is receiving a great deal of attention, given its profound detrimental implications for health and the burden it places upon the healthcare system. Body mass index (BMI) is perhaps the most commonly used measure for classifying subjects as either normal weight (18.5–24.9 kg/m2), overweight (25.0–29.9 kg/m2), or obese (≥30 kg/m2). While the BMI… View more
Author(s): Stuart W Zarich Added: 3 years ago
The clustering of cardiovascular (CV) risk factors associated with insulin is known as 'syndrome XÔÇÖ, the 'deadly quartetÔÇÖ, and 'dysmetabolic syndromeÔÇÖ among others. In addition to the clustering of obesity, hypertension (HTN), glucose intolerance, high triglycerides, and low high-density lipoprotein (HDL), other metabolic abnormalities have been associated with this syndrome, including… View more
Author(s): Allen B King , Gary S Wolfe Added: 3 years ago
Excess cardiovascular disease (CVD) with diabetes has been recognized for some time. Among diabetic individuals, CVD accounts for >50% of all deaths, and stroke accounts for an additional 15%.1 Diabetic women are at particularly high risk of CVD; diabetes eliminates the well-described female advantage for coronary disease mortality.2 This is alarming since the prevalence of type 2 diabetes is… View more
Author(s): Raif Tawakol Added: 3 years ago
Many patients on statin therapy understandably develop a false sense of security. They enjoy a lowered level of low-desity lipoprotein (LDL) and a risk reduction of some 35%. However, two out of three patients develop a myocardial infarction (MI) while on a statin therapy. Statins often do not increase HDL levels to any substantial degree (except for Rosuvastatin, which increases high-density… View more
Author(s): Andrew Choi , Jonathan S Steinberg , Suneet Mittal Added: 3 years ago
Atrial fibrillation (AF) is the most frequently observed sustained cardiac arrhythmia encountered in clinical practice. Its incidence is increasing in the US.1 Numerous risk factors have been implicated in the development of AF, including non-modifiable risk factors such as age and gender, modifiable risk factors such as obesity—itself a risk factor for obstructive sleep apnea (OSA)—and smoking,… View more
Author(s): Peter A McCullough Added: 3 years ago
Heart failure (HF) is a common condition and carries a considerable age-dependent all-cause mortality.1 As a leading cause of hospitalization in adults, ~50% of patients discharged with a diagnosis of HF are readmitted within six months, and the one-year mortality rate is 20% after an initial diagnosis is established. There is currently a chronic HF epidemic with a rapidly expanding prevalence… View more
Author(s): Raif Tawakol Added: 3 years ago
Many patients on statin therapy understandably develop a false sense of security. They enjoy a lowered level of low-desity lipoprotein (LDL) and a risk reduction of some 35%. However, two out of three patients develop a myocardial infarction (MI) while on a statin therapy. Statins often do not increase HDL levels to any substantial degree (except for Rosuvastatin, which increases high-density… View more