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Author(s): Alexandra Gonçalves , Carla Sousa , José Alberto de Agustín , et al Added: 3 years ago
Valvular disease is the most prevalent structural heart disease among adults and its burden is growing along with the increase in life expectancy.1 Mitral regurgitation (MR) is the second most frequent valvular disease, after aortic stenosis. Its natural history is very variable and highly dependent on the presence of symptoms. However, even in asymptomatic patients, the prognosis of severe MR is… View more
Author(s): Samir R Kapadia Added: 1 year ago
TCT 22 - In this short interview, Dr Samir Kapadia (Cleveland Clinic, OH, US) outlines the findings of the PROTECTED-TAVR trial, which aimed to demonstrate the performance of Boston Scientific's Sentinel® Cerebral Protection System in transcatheter aortic valve replacement. In this study, 3000 patients were randomized to receive either TAVR with the Sentinel system or TAVR without intervention… View more
Author(s): Astrid Apor , Andrea Nagy , Anikó Nagy , et al Added: 3 years ago
Abstract Mitral regurgitation (MR) is the most commonly found valvular lesion in echocardiography laboratories. Moderate and severe mitral regurgitation have proven to be associated with increased morbidity and mortality, and surgical reconstruction is recommended in severe cases whenever feasible. Three-dimensional echocardiography (3DE) is superior to conventional echocardiography in the… View more
Author(s): Usha Krishnan Added: 3 years ago
Pediatric interventional cardiology was born 40 years ago in 1966, when William Rashkind developed balloon septostomy in neonates with transposition of the great arteries.1 Almost a decade later, Andreas Gruentzig developed coronary angioplasty (between 1972 and 1976), which heralded an explosive era of interventional therapy for adults with heart disease, overshadowing the advances in… View more
Author(s): Colin M Barker , Michael J Reardon Added: 3 years ago
Aortic stenosis (AS) has a long latent period and then rapid progression with high mortality once symptoms appear.1 The absence of an effective medical therapy for symptomatic severe AS led to a class I indication for aortic valve replacement (AVR) in both the US and European guidelines.2,3 Unfortunately, a study by Bach et al. in 2009 found that up to half of patients with symptomatic severe AS… View more
Author(s): Miho Fukui , João L Cavalcante Added: 3 years ago
Degenerative calcific aortic stenosis (AS) is one of the most common valvular heart diseases, affecting >3% of those aged >65 years in the West.1 As a result of an aging population, the prevalence of AS is expected to increase. Severe AS causes chronic pressure overload of the left ventricle (LV), resulting in LV hypertrophy (LVH), diastolic dysfunction, an increase in the size of the left… View more
TCT Transcatheter Cardiovascular Therapeutics (TCT) is organised by Radcliffe Cardiology partner CardioVascular Research Foundation (CFR).TCT provides physicians opportunities for hands-on training, interactive learning, live case demonstrations, and to network, all with access to world-class KOLs and experts! View more