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Author(s): Enoch Akowuah Added: 1 year ago
ACC.23/WCC—DrEnoch Akowuah (James Cook University Hospital, UK) joins us to share the findings of the UK Mini-Mitral trial (National Institute of Health Research). This study is a multicentre, expertise-based randomised controlled trial that aimed to compare the safety and effectiveness of a minimally-invasive thoracotomy compared to conventional sternotomy in treating patients with degenerative… View more
Author(s): James De Lemos Added: 3 years ago
Acute coronary syndromes (ACS) is an umbrella term comprising a spectrum of clinical conditions ranging from unstable angina to non-ST elevation myocardial infarction and ST elevation myocardial infarction. ACS begins when an atherosclerotic plaque ruptures or erodes and a platelet-fibrin clot obstructs coronary blood flow. These critical disorders are a major cause of emergency medical care and… View more
Author(s): Shanmugam Uthamalingam , James L Januzzi Added: 3 years ago
Amino-terminal pro-B-type natriuretic peptide (NT-proBNP) is one of the natriuretic peptide family of hormones that play a vital role in the regulation of circulatory volume and pressure, reducing activity of the renin–angiotensin–aldosterone system and minimising myocardial fibrosis in the setting of heart muscle stretch. Therefore, natriuretic peptides exert favourable effects on the heart in… View more
Author(s): Leslee J Shaw , C Noel Bairey Merz , Steven E Reis , et al Added: 3 years ago
Recent findings from landmark clinical trials, such as the Women's Health Initiative (WHI)1,2, have significantly altered current thinking about the role of postmenopausal hormone therapy (HT) in cardiovascular disease (CVD) prevention. HT was a therapy widely accepted by women and physicians, often used for CVD prevention purposes, based on observational epidemiologic data and plausible… View more
Author(s): Shamai A Grossman Added: 3 years ago
Introduction Congestive heart failure (CHF) is an imbalance in pump function in which the heart fails to maintain the circulation of blood adequately. The most severe manifestation of CHF, pulmonary edema, develops when this imbalance causes an increase in lung fluid secondary to leakage from pulmonary capillaries into the interstitium and alveoli of the lung. CHF can be categorized as forward… View more
Author(s): James Gammie Added: 2 years ago
In this short interview, Dr James Gammie (University of Maryland Medical Center, MD, US) discusses the findings from surgical trial assessing the benefit of concomitant tricuspid repair during mitral valve surgery. The trial, presented at AHA 2021, demonstrated that at 2 years, TA had no impact on MACCE, survival, or QOL. Discussion Points 1. Reasoning for this Study 2. Study Design and… View more
Author(s): Jindrich Spinar , Lenka Spinarová Added: 3 years ago
Acute heart failure (AHF) is a major and growing cause of in-hospital mortality in developed countries. The prevalence of HF in an unselected population >45 years of age is estimated to be 2% and in a population >65 years of age is estimated to be 8.8%.1,2 The combination of aging of the population in many countries and improved survival after acute myocardial infarction has created rapid… View more
Author(s): Kilmer S McCully Added: 3 years ago
Discovery of the Homocysteine Theory of Arteriosclerosis The American biochemist Vincent DuVigneaud discovered a new amino acid in 1932 by treating methionine with sulfuric acid. The structure of this amino acid is similar to cysteine, except for one extra carbon atom, hence the name homocysteine. Subsequent investigation established the role of homocysteine as an intermediate in sulfur amino… View more
Author(s): Mirvat Alasnag Added: 5 months ago
TCT 23 - We are joined by Dr Mirvat Alasnag (The King Fahd Armed Forces Hospital, SA) for an insightful summary of the late-breaking trials that are expected to have an impact on interventional science and clinical practice. Trials covered in detail include: Agent IDE ALIGN-AR PARTNER 3 EVOLUT Low-Risk TRISCEND Recorded remotely from Jeddah, 2023. Editor: Jordan Rance Video Specialist:… View more
Author(s): Bijoy K Khandheria Added: 3 years ago
Cardiovascular ultrasound is an established imaging modality in the practice of cardiovascular disease (CVD), whether this is provided by a CV specialist or health professionals with training in internal medicine. Transthoracic imaging wherein the transducer is placed on the chest wall has some limitations. These include inadequate quality of images resulting in poor informationÔÇöapproximately 5… View more