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Author(s): Keith C Ferdinand Added: 3 years ago
Hypertension remains a prevalent, major risk factor for cardiovascular disease (CVD), affecting over one-third of adults in the uS—nearly 74 million people.1 In the uS, elevated blood pressure (BP) contributes to 69% of first myocardial infarctions (MIs), 74% of cases of congestive heart failure (CHF), and 77% of first strokes.1 The total direct and indirect cost of CVD and stroke in the US for… View more
Author(s): Shawna D Nesbitt Added: 3 years ago
The prevalence of hypertension is increasing. Most recently National Health and Nutrition Examination Survey (NHANES) 2003-2004 report showed that awareness of hypertension is quite high and increasing across all age and ethnic groups.1 Encouragingly, treatment and control are improving in the elderly population; however, treatment and control in younger age groups has not shown the same success… View more
Author(s): Domenic A Sica Added: 3 years ago
Diabetes mellitus is rapidly increasing in its worldwide prevalence and is currently estimated to affect 7-8% of the US population.1 In 2005, 1.5 million new cases of diabetes were diagnosed in people aged 20 years or older in the US. In the not-so-distant past, type 2 diabetes mellitus was viewed as a seemingly benign condition, at least in the elderly, with little effect on life expectancy and… View more
Author(s): Stefan H Hohnloser Added: 3 years ago
Atrial fibrillation (AF) is the most common cardiac arrhythmia, and is associated with a five-fold increase in the risk of stroke and embolism.1 Oral anticoagulation (OAC) with warfarin reduces stroke by two-thirds compared with no treatment.1–3 Compared with aspirin, OAC reduces the risk of stroke by 45% and reduces cardiovascular events by 29%.4 However, it increases the risk of major bleeding… View more
Author(s): Meshal Soni , Edo Y Birati Added: 3 years ago
The history of documented heart failure in medical literature dates back as early as the late 1700s, when William Withering recognized the therapeutic use of foxglove in patients with “dropsy”. The extract from the foxglove plant contained the cardiac glycoside digitalis, and edema – known as “dropsy” – was described in patients we now presume had the clinical syndrome of heart failure.1 Over the… View more
Author(s): Andrew Choi , Jonathan S Steinberg , Suneet Mittal Added: 3 years ago
Atrial fibrillation (AF) is the most frequently observed sustained cardiac arrhythmia encountered in clinical practice. Its incidence is increasing in the US.1 Numerous risk factors have been implicated in the development of AF, including non-modifiable risk factors such as age and gender, modifiable risk factors such as obesity—itself a risk factor for obstructive sleep apnea (OSA)—and smoking,… View more
Author(s): Gerald V Naccarelli Added: 3 years ago
Atrial fibrillation (AF) continues to be the most common arrhythmic disorder that is admitted to the hospital in the Medicare population. Over the next five years, the worldwide AF market potential will grow to in excess of 8.5 million people. This growth is predominantly fueled by the aging of the worldwide population and the fact that AF is an affliction of the aged with up to 6% of… View more
Author(s): Otto A Smiseth , Anders Opdahl , Espen Boe , et al Added: 3 years ago
Abstract Heart failure with preserved left ventricular ejection fraction (HF-PEF), sometimes named diastolic heart failure, is a common condition most frequently seen in the elderly and is associated with arterial hypertension and left ventricular (LV) hypertrophy. Symptoms are attributed to a stiff left ventricle with compensatory elevation of filling pressure and reduced ability to increase… View more
Author(s): James A Reiffel Added: 3 years ago
Atrial fibrillation (AF) is the most frequent serious arrhythmia encountered in clinical practice. It is usually symptomatic; can reduce quality of life; commonly results in hospitalization; typically requires multiple drugs in its treatment; and can result in heart failure, embolization and its consequences, and death. Even when AF itself does not directly provoke symptoms leading to its… View more
Author(s): Jack Collier , Arthur J Labovitz Added: 3 years ago
The approach to the treatment of a variety of cardiovascular disorders has undergone remarkable change over the past two decades. The use of both percutaneous interventions in patients with acute myocardial infarction and automatic implantable cardiodefibrillators in patients with ventricular arrhythmias represent important examples. The cardiology community is currently in the process of another… View more