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Author(s): Peter J Fitzgerald , Martin B Leon Added: 3 years ago
An unintended consequence of the market success of drug-eluting stents has been a growing concern about their safety and safety-related costs. These devices have been so quickly and widely adopted that their market penetration already equals that of some of the most popular pharmaceutical drugs. Consequently, the absolute significance of even a low incidence of side effects becomes magnified by… View more

Intervention
Author(s): Peter J Fitzgerald , Martin B Leon Added: 3 years ago
An unintended consequence of the market success of drug-eluting stents has been a growing concern about their safety and safety-related costs. These devices have been so quickly and widely adopted that their market penetration already equals that of some of the most popular pharmaceutical drugs. Consequently, the absolute significance of even a low incidence of side effects becomes magnified by… View more

Intervention
Overview of Quantitative Flow Ratio and Optical Flow Ratio in the Assessment of Intermediate Coronary Lesions
Author(s): Jelmer Westra , Shengxian Tu Added: 3 years ago
Physiological lesion assessment is recommended for the identification of intermediate coronary lesions that might benefit from percutaneous coronary intervention (PCI).1 The quantitative flow ratio (QFR) was developed to derive coronary physiology from angiographic images, whereas the optical flow ratio (OFR) is a more recent approach for the rapid and automated assessment of coronary physiology… View more

Intervention
Author(s): William T Brinkman , Wilson Y Szeto , Joseph E Bavaria Added: 3 years ago
The introduction of endovascular stent graft technology has ushered in a new era in therapy for diseases of the descending thoracic aorta. This ‘radical and revolutionary’ stent graft technology has been accompanied by simultaneous advances in non-invasive imaging and materials technology. The technical challenges of stent graft deployment in the descending thoracic aorta—such as proximity to the… View more

Intervention
ESC 23: Day 1 Wrap-Up with Dr Alasnag and Dr Al-Shaibi
Author(s): Mirvat Alasnag , Khaled Al-Shaibi Added: 7 months ago
ESC 23 — We are joined by Dr Mirvat Alasnag and Dr Khaled Al-Shaibi (The King Fahd Armed Forces Hospital, SA) for an insightful wrap-up of the first day of ESC Congress 2023. Trials covered in detail include: New ESC Guidelines for 2023 - 00:24 - 10:03 STEP-HFpEF - 10:04 - 12:03 COP-AF - 12:04 - 13:11 Recorded on-site at ESC Congress 2023, Amsterdam. Editors: Mirjam Boros and Jordan… View more

Standards & Guidelines

Electrophysiology & Arrhythmia
ESC 23: Day 2 Wrap-Up with Dr Alasnag and Dr Al-Shaibi
Author(s): Mirvat Alasnag , Khaled Al-Shaibi Added: 7 months ago
ESC 23 — We are joined by Dr Mirvat Alasnag and Dr Khaled Al-Shaibi (The King Fahd Armed Forces Hospital, SA) for an insightful wrap-up of the first day of ESC Congress 2023. New data releases covered in detail include: BUDAPEST-CRT FIRE ECLS-SHOCK STOP-DAPT 3 Recorded on-site at ESC Congress 2023, Amsterdam. Editors: Mirjam Boros and Jordan Rance Video Specialists: Dan Brent, Tom… View more

Intervention
Author(s): Bill D Gogas , Jun-Jie Zhang , Shao-Liang Chen Added: 3 years ago
The current generation of drug-eluting stents (DES) that are clinically available in the US represent significant advancements compared to angioplasty, bare metal stents, and the first generation of DES. The Xience everolimus-eluting stents (Abbott Vascular), Promus everolimus-eluting stents (Boston Scientific) and Resolute zotarolimus-eluting stents (Medtronic) demonstrate the optimal balance of… View more

Intervention
Author(s): Shane Prejean , Todd M Brown Added: 3 years ago
Proprotein convertases are proteolytic enzymes that activate proteins by post-translational alterations in protein structure. Proprotein convertase subtilisin/kexin 9 (PCSK9) is a proprotein convertase that binds and inactivates the low-density lipoprotein (LDL) receptor on the surface of hepatocytes resulting in higher levels of serum LDL cholesterol (LDL-C).1 Over-expression of PCSK9 leads to a… View more

Prevention & Chronic Conditions
Author(s): Albert Alahmar , Anthony H Gershlick Added: 3 years ago
Drug-eluting stents (DES) have revolutionized the field of interventional cardiology. The US Food and Drug Administration (FDA) is expecting that the total number of DES implanted in 2010 will surpass 5 million worldwide. Although initial results seemed promising, longer-term follow-up in a wider range of patients revealed some concerns. Enhanced platelet aggregation, delayed neointimal growth, a… View more

Intervention
Feasibility, Safety, and Clinical Performance of Self-apposing Stents for Left Main Stenosis
Author(s): Krzysztof Pujdak , Jan Kähler , Marc Werner Added: 3 years ago
Significant stenosis of the left main (LM) coronary artery is observed in 7% of coronary angiographies.1 Coronary artery bypass grafting has traditionally been the treatment of choice. In recent years, percutaneous coronary intervention (PCI) has evolved as an alternative, especially for low and intermediate SYNTAX score patients.2 However, during PCI of bifurcation lesions, approximately 50% of… View more

Intervention