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Author(s): Somsupha Kanjanauthai , Kabir Bhasin , Luigi Pirelli , et al Added: 3 years ago
Transcatheter aortic valve replacement (TAVR) has been established as a therapeutic option for patients with severe symptomatic aortic stenosis who are considered to be of intermediate, high or prohibitive surgical risk.1–5 As a result of favorable TAVR outcomes and substantial improvements in transcatheter heart valve (THV) technologies and implantation techniques, the feasibility of broadening… View more
Author(s): Kendra J Grubb Added: 1 year ago
Dr Kendra Grubb (Emory Structural Heart and Valve Center, GA, US) outlines the interim analysis of the Optimize PRO Study (NCT04091048), originally presented at EuroPCR 2022. Optimize PRO aimed to evaluate valve performance and procedural outcomes of optimised TAVR care using Medtronic's Evolut™ PRO and Evolut™ PRO+ devices. Findings are promising and show that no patients experienced a… View more
Author(s): Aniket S Rali , Andrew J Sauer Added: 3 years ago
In late December 2019, an outbreak of an unknown disease called a pneumonia of uncertain cause occurred in Wuhan, Hubei Province, China.1 Over the next few days, several independent laboratories identified the causative agent as a novel coronavirus.2–4 The WHO has temporarily named this virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the related infectious disease… View more
Author(s): Steven R Sigman Added: 3 years ago
Although less common than other forms of cardiomyopathy, cardiac sarcoidosis (CS), both as part of a systemic process and in its isolated form, is an important, and increasingly recognized disorder. This is felt to be due, in part, to advances in cardiac imaging and heightened awareness of the disorder.1,2 CS is associated with high rates of morbidity and mortality, including sudden cardiac death… View more
Author(s): Colin M Barker , Michael J Reardon Added: 3 years ago
Aortic stenosis (AS) has a long latent period and then rapid progression with high mortality once symptoms appear.1 The absence of an effective medical therapy for symptomatic severe AS led to a class I indication for aortic valve replacement (AVR) in both the US and European guidelines.2,3 Unfortunately, a study by Bach et al. in 2009 found that up to half of patients with symptomatic severe AS… View more
Author(s): Jagmeet P Singh Added: 3 years ago
Cardiac resynchronization therapy (CRT) has achieved widespread approval as a safe and efficient therapeutic strategy for medically refractory congestive heart failure (CHF). The standard indications for CRT include patients with advanced heart failure and evidence of systolic dysfunction (ejection fraction [EF] ≤35%), conduction tissue disease (QRS duration ≥120ms), and marked cardiac symptoms … View more
Author(s): Lori L McMullan , Gaston Vergara , Nassir F Marrouche Added: 3 years ago
Atrial fibrillation (AF) and heart failure (HF) are two disease conditions that are intimately intertwined, both pathophysiologically and clinically. Currently, over 2.3 million people in North America and 4.5 million in the EU have AF, making it the most common arrhythmia encountered in clinical practice.1,2 It is expected that by 2050 there will be over 10 million people with AF.3 The estimated… View more