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HFA 23: APOLLO-B: Patisiran Treatment for Cardiac Amyloidosis
Author(s): Marianna Fontana Added: 11 months ago
ESC-HFA 23 — We are joined by Prof Marianna Fontana (University College London, UK), as she outlines the key findings from the phase 3 APOLLO-B study (Alnylam Pharmaceuticals) (NCT03997383). APOLLO-B investigated the use of patisiran, a transthyretin-directed small interfering RNA, in a cohort of patients with cardiac amyloidosis. 360 patients were enrolled in the trial and were randomized 1:1… View more

Heart Failure
ACC 23 Expert Consensus Decision Pathway on Cardiac Amyloidosis: Highlights
Author(s): Michelle Kittleson Added: 1 year ago
Dr Michelle Kittleson (Cedars-Sinai California Heart Center, US) provides an overview of the 2023 ACC Expert Consensus Decision Pathway on Comprehensive Multidisciplinary Care for the Patient with Cardiac Amyloidosis.Dr Kittleson highlights the unmet needs in managing patients with cardiac amyloidosis and stresses the importance of a multidisciplinary approach involving cardiologists,… View more

Standards & Guidelines

Heart Failure
Carol J. Whelan
Research Area(s) / Expertise:

Heart Failure

Imaging

Cardio-oncology

Amyloidosis

 Job title: Consultant Cardiologist, National Amyloidosis Centre & Royal Free London Hospital, University College London, UK
In October 2009, the Royal Free London NHS Foundation Trust hired Dr. Carol Whelan as a consultant cardiologist with expertise in imaging, heart failure, and cardiac amyloidosis. As a result of her efforts at the National Amyloidosis Centre, she has been given the title of Honorary Associate Professor at UCL. In 2011, she was named the hospital's clinical lead for heart failure. In 2018, she was… View more
Author(s): Yaser Nemshah , Alex Clavijo , Gyanendra Sharma Added: 3 years ago
Amyloidosis is a heterogenous group of disorders that develops secondary to the deposition of abnormally folded proteins, amyloid fibrils, in the extracellular space. Amyloidosis is classified according to the type of the precursor protein that results in the formation of amyloid fibrils. It can be inherited or acquired, and can involve multiple organs, including the heart. Amyloidosis that… View more

Heart Failure
Margot K Davis
Job title: Director, University of British Columbia (UBC) Cardiology-Oncology Program, Vancouver General Hospital, Vancouver, Canada
Dr Margot Davis is a cardiologist at Vancouver General Hospital and St. Paul's Hospital, as well as the director of the UBC Cardiology-Oncology Program and a clinical assistant professor at the University of British Columbia (UBC). Dr Davis is a key panel member of the CCS Cardio-Oncology Guidelines, a secondary panel member of the CCS Heart Failure Guidelines, and co-chair of the CCS/CHFS… View more
Job title: Professor of Cardiology and Honorary Consultant Cardiologist
ProfMarianna Fontana isProfessor of Cardiology and Honorary Consultant Cardiologistat the National Amyloidosis Centre, Division of Medicine,University College London, London, UK. Her main clinical and research interests include the delivery of efficient and effective care for patients with amyloidosis, with a particular focus on new technologies. View more
Kathleen Zhang
Research Area(s) / Expertise:

Cardio-oncology

 Job title: Assistant Professor, Department of Internal Medicine, UT Southwestern Medical Center, Fort Worth, US
Dr Kathleen Zhang works as an assistant professor in the UT Southwestern Medical Center's department of internal medicine. She is an expert in cardio-oncology, the treatment of cancer patients' cardiovascular systems.Dr Zhang obtained her medical degree from the University of Pennsylvania, where she also completed her residency in internal medicine. Her specialized training in cardiology and… View more
Barry H Trachtenberg
Research Area(s) / Expertise:

Cardio-oncology

Amyloidosis

Heart Failure

 Job title: Heart Failure Cardiologist
Barry Trachtenberg, MD, is a cardiologist specialising in Heart Failure/Transplant Cardiology, Cardio-Oncology, and Cardiac Amyloidosis at Houston Cardiovascular Associates. Dr Trachtenberg served as the Program Director of Advanced HF Fellowship and Director of the Cardio-Oncology Program at Houston Methodist. He completed his medical degree at the University of Texas Health Science Center… View more
Michelle Kittleson
Research Area(s) / Expertise:

Amyloidosis

Heart Failure

 Job title: Cardiologist & Professor of Medicine
Dr MichelleKittlesonis Professor of Medicine at Cedars-Sinai and Director of Education in Heart Failure and Transplantation at the Smidt Heart Institute. She graduated from Harvard College and received her medical degree from Yale University. She completed residency training at Brigham and Women's Hospital and cardiology fellowship at Johns Hopkins, where she also received a PhD in Clinical… View more
Research Area(s) / Expertise:

Cardio-oncology

Amyloidosis

Heart Failure

 Job title: Chair, Cardio-oncology Clinic, Santa Casa de Sao Paulo, Sao Paulo, Brazil
Dr Macedo is a researcher at the Brazilian Clinical Research Institute (BCRI), located in Sao Paulo, Brazil, and the chair of the cardio-oncology clinic at Santa Casa de Sao Paulo. She specialises in heart failure, thrombosis, amyloidosis and the cardiovascular effects of anti-cancer treatment. She obtained both an MD and a Master's in Health Science from the University of Minas Gerais in Brazil. View more