Search results
Author(s):
Stéphane G Carlier
,
Kaoru Tanaka
,
Amin Katouzian
Added:
3 years ago
Most cases of myocardial infarction and stroke occur when a thrombus is formed on a previously stable plaque that ruptures.1 Persons at risk typically have no premonitory symptoms, and angiographic studies of coronary arteries in patients with non-fatal acute coronary syndromes (ACS) showed that most such events are due to rapid progression of mild, hemodynamically insignificant lesions.2–4…
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ACC 22: Secondary Analysis of CANTOS Finds LDL & HDL Predict Residual Risk of Atherosclerotic Events
Author(s):
Paul M Ridker
Added:
1 year ago
Video
Author(s):
Michelle O'Donoghue
Added:
7 months ago
ESC 23 — Dr Michelle O'Donoghue (Brigham and Women's Hospital, US) outlines a trial update from OCEAN(a)-Dose Extension trial (NCT05581303) in this succinct interview.
OCEAN(a)-DOSE (Amgen) was a dose-finding study aiming to evaluate a siRNA, olpasiran, and its effect on risk for coronary heart disease death, myocardial infarction or urgent coronary revascularization when administered…
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Author(s):
Marc Sirol
Added:
3 years ago
Atherosclerosis and its thrombotic complications are the first cause of mortality and morbidity in industrialized countries. Furthermore, despite pharmacological intervention and lifestyle changes, cardiovascular disease (CVD) continues to be the principal cause of death in the US. Despite great advances in the understanding of the initiation and progression of atherosclerosis and its risk…
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Author(s):
Marc Sirol
Added:
3 years ago
Atherosclerosis and its thrombotic complications are the first cause of mortality and morbidity in industrialized countries. Furthermore, despite pharmacological intervention and lifestyle changes, cardiovascular disease (CVD) continues to be the principal cause of death in the US.1 Despite great advances in the understanding of the initiation and progression of atherosclerosis and its risk…
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Author(s):
Christopher M Kramer
Added:
3 years ago
Atherosclerosis is a systemic disease that can silently affect the entire vascular system and often manifests clinically as stroke, myocardial infarction or sudden cardiac death. Despite advances in diagnosis and treatment, the sequelae of atherosclerosis remain the leading cause of death in adult Americans. Traditionally the gold standard for the diagnosis and assessment of atherosclerosis…
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Joerg Herrmann
Research Area(s) / Expertise:
Job title: Director, Cardio-Oncology Clinic, Mayo Clinic, Rochester, US
Author
Author(s):
Jean-Claude Tardif
,
Therese Heinonen
Added:
3 years ago
Atherosclerotic cardiovascular disease is the result of a continuous and deleterious interaction between components of the vascular wall and the circulating blood. Circulating lipids and lipoproteins play a significant role in the initiation of fatty streaks and the subsequent progression to complex and vulnerable atherosclerotic plaques. The important role that circulating lipids play in…
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Author(s):
Gurleen Kaur
,
Michelle O'Donoghue
Added:
1 year ago
AHA 22 - Dr Gurleen Kaur (Brigham and Women's Hospital, US) joins us in this collaboration between @CardioNerds and Radcliffe Cardiology to interview OCEAN(a)'s primary investigator, DrMichelle O'Donoghue (Brigham and Women's Hospital, US) on the late-breaking data revealed at AHA.
OCEAN(a) was a dose-finding study that aimed to evaluate an siRNA, olpasiran's (Amgen) effect administered…
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Author(s):
Atsushi Sakamoto
,
Anne Cornelissen
,
Yu Sato
,
et al
Added:
2 years ago