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Author(s): Nico A Blom Added: 3 years ago
Cardiac resynchronization therapy (CRT) using biventricular pacing has been proven to be effective in adult patients with left ventricular (LV) systolic dysfunction and QRS prolongation. In this group of patients, CRT improves exercise tolerance, symptoms of heart failure and all-cause mortality.1 In addition, there is growing evidence that inter- and intra-ventricular dyssynchrony induced by… View more
Author(s): Hou Tee Lu , Rusli Bin Nordin , Aizai Azan Bin Abdul Rahim Added: 3 years ago
Heart failure (HF) is a global public health problem, affecting an estimated 26 million people worldwide and resulting in more than 1 million hospitalizations annually in the US and Europe.1 This HF pandemic is also evident in Asia and other parts of the world.2–4 Although the outcomes for HF patients have improved with the discovery of multiple evidence-based drug and device therapies,… View more
Author(s): Yugo Yamashita Added: 8 months ago
What's hot at the European Society of Cardiology (ESC) Congress 2023? Browse our curated coverage of the latest updates in cardiology from Amsterdam. Watch ourView From the Thoraxcenterseries for a concise line up of the most awaited trials fromProf Nicolas Van MieghemandDr Joost Daemen. For a deeper dive into key clinical trial data and its applicability, host,Dr Harriette Van… View more
Author(s): Aniket S Rali , Andrew J Sauer Added: 3 years ago
In late December 2019, an outbreak of an unknown disease called a pneumonia of uncertain cause occurred in Wuhan, Hubei Province, China.1 Over the next few days, several independent laboratories identified the causative agent as a novel coronavirus.2–4 The WHO has temporarily named this virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the related infectious disease… View more
Author(s): Alan S Maisel Added: 3 years ago
Acute coronary syndrome (ACS) and congestive heart failure (CHF) are significant health risks affecting a large part of the population. In both diseases, early detection and initiation of treatment significantly reduce the risk of serious adverse events and death. B-type natriuretic peptide (BNP) and myeloperoxidase (MPO) have both shown considerable utility in the early diagnosis of patients… View more
Author(s): Amarinder Bindra , Shelley A Hall Added: 3 years ago
After a drought in viable new therapies for more than a decade, two new drugs for use in heart failure patients were approved by the US Food and Drug Administration (FDA) in 2015. These drugs represent two new classes of agents in the heart failure space: a combined angiotensin receptor-neprilysin inhibitor (ARNI) (sacubitril/valsartan; brand name Entresto®, Novartis) and a sinoatrial node… View more
Job title: Distinguished Scholar in Cardiovascular Science
Personal History Dr Milton Packer was born to Polish immigrants in 1951 and raised in Philadelphia, US. Prior to studying medicine, he was politically active in the 1960s. In his words: “The focus of my upbringing was education, but the major guiding principle in my childhood years (and throughout my entire life) was an uncompromising sense of justice. I was always imbued with the need to… View more
Author(s): Otto A Smiseth , Anders Opdahl , Espen Boe , et al Added: 3 years ago
Abstract Heart failure with preserved left ventricular ejection fraction (HF-PEF), sometimes named diastolic heart failure, is a common condition most frequently seen in the elderly and is associated with arterial hypertension and left ventricular (LV) hypertrophy. Symptoms are attributed to a stiff left ventricle with compensatory elevation of filling pressure and reduced ability to increase… View more
Author(s): Biswajit Kar , Reynolds M Delgado III Added: 3 years ago
Cardiogenic shock (CGS) results in inadequate end organ perfusion and is associated with high mortality. For patients presenting with CGS following myocardial infarction (MI), reported rates of mortality range between 55% and 80% despite aggressive pharmacological therapy and use of the intra-aortic balloon pump (IABP). Patients with CGS due to ventricular septal defect (VSD) or ventricular… View more
Author(s): Emily Seif , Leway Chen , Bruce Goldman Added: 3 years ago
Myocarditis is an inflammatory disease of the myocardium. It has a wide spectrum of severity, with symptoms ranging from mild fevers, shortness of breath, and palpitations to severe hemodynamic collapse. Fulminant myocarditis is a rare form of severe myocarditis that presents with sudden-onset acute heart failure, cardiogenic shock, or life-threatening arrhythmias.1 Prognosis and management of… View more